Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 353801..353985 Replicon chromosome
Accession NZ_CP094768
Organism Staphylococcus aureus strain IVB6202

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag MUA94_RS01630 Protein ID WP_000482647.1
Coordinates 353801..353908 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 353925..353985 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA94_RS01605 (MUA94_01600) 349163..349636 + 474 WP_000456493.1 GyrI-like domain-containing protein -
MUA94_RS01610 (MUA94_01605) 349759..350970 - 1212 WP_001191923.1 multidrug effflux MFS transporter -
MUA94_RS01615 (MUA94_01610) 351152..351811 - 660 WP_262538147.1 hypothetical protein -
MUA94_RS01620 (MUA94_01615) 351871..353013 - 1143 WP_262538149.1 glycerate kinase -
MUA94_RS01625 (MUA94_01620) 353281..353667 + 387 WP_000779353.1 flippase GtxA -
MUA94_RS01630 (MUA94_01625) 353801..353908 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 353925..353985 - 61 - - Antitoxin
MUA94_RS01635 (MUA94_01630) 354612..356375 + 1764 WP_262538151.1 ABC transporter ATP-binding protein -
MUA94_RS01640 (MUA94_01635) 356400..358133 + 1734 Protein_325 ABC transporter ATP-binding protein/permease -
MUA94_RS01645 (MUA94_01640) 358364..358531 + 168 WP_001789205.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T240266 WP_000482647.1 NZ_CP094768:353801-353908 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T240266 NZ_LS992185:c1320693-1320475 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 61 bp

>AT240266 NZ_CP094768:c353985-353925 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References