Detailed information of TA system TA240203

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2212910..2213126
• Replicon: chromosome
• Accession: NZ_CP094755
• Organism: Staphylococcus aureus strain IVB6242

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MUA32_RS11050
• Protein ID: WP_073392962.1
• Coordinates: 2213022..2213126 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2212910..2212965 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA32_RS11025	2209104..2209769	-	666	WP_001024099.1	SDR family oxidoreductase	-
MUA32_RS11030	2209921..2210241	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MUA32_RS11035	2210243..2211223	+	981	WP_262515911.1	CDF family zinc efflux transporter CzrB	-
MUA32_RS11040	2211489..2212580	+	1092	WP_000495684.1	hypothetical protein	-
-	2212910..2212965	+	56	-	-	Antitoxin
MUA32_RS11050	2213022..2213126	-	105	WP_073392962.1	hypothetical protein	Toxin
MUA32_RS11055	2213806..2213964	+	159	WP_001792784.1	hypothetical protein	-
MUA32_RS11060	2214623..2215480	-	858	WP_000370937.1	HAD family hydrolase	-
MUA32_RS11065	2215548..2216330	-	783	WP_262515912.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3920.80 Da
• Isoelectric Point: 5.5724

>T240203 WP_073392962.1 NZ_CP094755:c2213126-2213022 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T240203 NZ_LS992175:4101196-4101537 [Citrobacter freundii]
ATGAAAACTTTACCTGCAACAACTCAGCGGGCGGTGAAGCCCTGCCTGTCACCCGTGGCTGTCTGGCAAATGTTACTGAC
ACGTCTGCTGGAACAGCACTATGGTCTGACAATAAACGACACGCCATTCTGCAATGAGGCTGTGATTAAGGAACACATCG
ATGCCGGTATCACCCTAGCCGATGCCGTGAATTTTCTGGTAGAAAAATACGAGCTGGTTCGTATAGACAGGAAGGGATTT
AGCTGGCAGGAACAATCTCCTTATCTCCGGGCTGTAGACATTCTGCGAGCGCGGCAGGCAACTGGCTTGTTGCGGCAAAG
CCGTAACAACGTAGTACGATGA

Antitoxin

Nucleotide

• Length: 56 bp

>AT240203 NZ_CP094755:2212910-2212965 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin