Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2212907..2213123 Replicon chromosome
Accession NZ_CP094752
Organism Staphylococcus aureus strain IVB6243

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag MUA86_RS11055 Protein ID WP_073392962.1
Coordinates 2213019..2213123 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2212907..2212962 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MUA86_RS11030 2209101..2209766 - 666 WP_001024099.1 SDR family oxidoreductase -
MUA86_RS11035 2209918..2210238 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
MUA86_RS11040 2210240..2211220 + 981 WP_262515911.1 CDF family zinc efflux transporter CzrB -
MUA86_RS11045 2211486..2212577 + 1092 WP_000495684.1 hypothetical protein -
- 2212907..2212962 + 56 - - Antitoxin
MUA86_RS11055 2213019..2213123 - 105 WP_073392962.1 hypothetical protein Toxin
MUA86_RS11060 2213803..2213961 + 159 WP_001792784.1 hypothetical protein -
MUA86_RS11065 2214620..2215477 - 858 WP_000370937.1 HAD family hydrolase -
MUA86_RS11070 2215545..2216327 - 783 WP_262515912.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T240185 WP_073392962.1 NZ_CP094752:c2213123-2213019 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T240185 NZ_LS992171:3472803-3473021 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 56 bp

>AT240185 NZ_CP094752:2212907-2212962 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References