Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | txpA-SprF3/- |
| Location | 1590603..1590894 | Replicon | chromosome |
| Accession | NZ_CP094747 | ||
| Organism | Staphylococcus aureus strain IVB6249 | ||
Toxin (Protein)
| Gene name | txpA | Uniprot ID | - |
| Locus tag | MUA08_RS07720 | Protein ID | WP_252559492.1 |
| Coordinates | 1590718..1590894 (-) | Length | 59 a.a. |
Antitoxin (RNA)
| Gene name | SprF3 | ||
| Locus tag | - | ||
| Coordinates | 1590603..1590659 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MUA08_RS07680 (MUA08_07680) | 1585678..1585830 | - | 153 | WP_172609139.1 | hypothetical protein | - |
| MUA08_RS07685 (MUA08_07685) | 1585817..1586731 | - | 915 | WP_000476887.1 | DUF1672 domain-containing protein | - |
| MUA08_RS07690 (MUA08_07690) | 1586789..1587694 | - | 906 | WP_000913238.1 | DUF1672 domain-containing protein | - |
| MUA08_RS07695 (MUA08_07695) | 1587784..1587999 | - | 216 | WP_262518166.1 | hypothetical protein | - |
| MUA08_RS07700 (MUA08_07700) | 1588812..1589303 | - | 492 | WP_252559491.1 | staphylokinase | - |
| MUA08_RS07705 (MUA08_07705) | 1589493..1590248 | - | 756 | WP_252559490.1 | CHAP domain-containing protein | - |
| MUA08_RS07710 (MUA08_07710) | 1590260..1590514 | - | 255 | WP_238522769.1 | phage holin | - |
| MUA08_RS07715 (MUA08_07715) | 1590566..1590666 | + | 101 | Protein_1514 | hypothetical protein | - |
| - | 1590603..1590659 | + | 57 | - | - | Antitoxin |
| MUA08_RS07720 (MUA08_07720) | 1590718..1590894 | - | 177 | WP_252559492.1 | type I toxin-antitoxin system toxin PepG1 | Toxin |
| MUA08_RS07725 (MUA08_07725) | 1591095..1591874 | - | 780 | WP_262518171.1 | exotoxin | - |
| MUA08_RS07730 (MUA08_07730) | 1592329..1592703 | - | 375 | WP_252559488.1 | hypothetical protein | - |
| MUA08_RS07735 (MUA08_07735) | 1592759..1593046 | - | 288 | WP_162636283.1 | hypothetical protein | - |
| MUA08_RS07740 (MUA08_07740) | 1593092..1593244 | - | 153 | WP_001153681.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | sak / sea / gnd | 1584683..1656917 | 72234 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6818.48 Da Isoelectric Point: 10.9678
>T240149 WP_252559492.1 NZ_CP094747:c1590894-1590718 [Staphylococcus aureus]
MDRWRLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSIKK
MDRWRLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSIKK
Download Length: 177 bp
>T240149 NZ_LS992168:1885460-1885711 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGACAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGACAAAGGAACGGAAAAGGAC
ATTATTGAGTGA
Antitoxin
Download Length: 57 bp
>AT240149 NZ_CP094747:1590603-1590659 [Staphylococcus aureus]
AAAAGGGCAACATGCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC
AAAAGGGCAACATGCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
