Detailed information of TA system TA240048

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-sprA1AS/-
• Location: 979790..979951
• Replicon: chromosome
• Accession: NZ_CP094715
• Organism: Staphylococcus pasteuri strain IVB6198

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: -
• Locus tag: MUA61_RS04860
• Protein ID: WP_107999723.1
• Coordinates: 979790..979885 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	979917..979951 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MUA61_RS04850 (MUA61_04850)	975725..978658	+	2934	WP_262552931.1	AAA family ATPase	-
MUA61_RS04855 (MUA61_04855)	978658..979599	+	942	WP_017638040.1	3'-5' exoribonuclease YhaM	-
MUA61_RS04860 (MUA61_04860)	979790..979885	+	96	WP_107999723.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	979917..979951	-	35	-	-	Antitoxin
MUA61_RS04865 (MUA61_04865)	980045..981037	-	993	WP_029056284.1	peptidylprolyl isomerase	-
MUA61_RS04870 (MUA61_04870)	981220..981777	-	558	WP_029056283.1	DUF3267 domain-containing protein	-
MUA61_RS04875 (MUA61_04875)	981973..982344	-	372	WP_017638293.1	YtxH domain-containing protein	-
MUA61_RS04880 (MUA61_04880)	982422..982847	-	426	WP_017638294.1	HIT family protein	-
MUA61_RS04885 (MUA61_04885)	982979..983719	+	741	WP_070454050.1	ABC transporter ATP-binding protein	-
MUA61_RS04890 (MUA61_04890)	983712..984935	+	1224	WP_029056282.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (3-109)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3656.34 Da
• Isoelectric Point: 8.0878

>T240048 WP_107999723.1 NZ_CP094715:979790-979885 [Staphylococcus pasteuri]
MSEIFVHIMTTVISGCIVTLFAHWLRHRNDK

Nucleotide

• Length: 96 bp

>T240048 NZ_LS483482:982665-983015 [Staphylococcus lugdunensis]
ATGATTAGACGCGGCGATGTATATTTAGCTGATTTATCACCGGTACAAGGGTCTGAACAAGGGGGAGTAAGACCAGTTGT
CATCATTCAAAATGACACCGGTAATAAATATAGTCCAACTGTAATTGTAGCTGCAATTACTGGAAGGATTAATAAAGCGA
AAATACCCACTCATGTGGAAATAGGTAAAAAGAAATATAAGTTAGATAAAGATTCTGTTATTCTGTTAGAGCAAATACGA
ACATTAGATAAAAAAAGATTAAAAGAAAAACTTACTTATCTCTCTGAGGATAAAATGAAAGAAGTAGATCATGCCCTAGA
CATTAGTCTAGGTTTACATAACTATCATTAA

Antitoxin

Nucleotide

• Length: 35 bp

>AT240048 NZ_CP094715:c979951-979917 [Staphylococcus pasteuri]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin