Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
| Location | 9181..9340 | Replicon | plasmid unnamed |
| Accession | NZ_CP094703 | ||
| Organism | Staphylococcus simulans strain IVB6209 | ||
Toxin (Protein)
| Gene name | sprA1 | Uniprot ID | - |
| Locus tag | MUA41_RS12995 | Protein ID | WP_262556599.1 |
| Coordinates | 9181..9276 (+) | Length | 32 a.a. |
Antitoxin (RNA)
| Gene name | sprA1AS | ||
| Locus tag | - | ||
| Coordinates | 9304..9340 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MUA41_RS12960 (4377) | 4377..5582 | - | 1206 | WP_262556591.1 | sodium/glutamate symporter | - |
| MUA41_RS12965 (6013) | 6013..6213 | + | 201 | WP_262556594.1 | cold-shock protein | - |
| MUA41_RS12970 (6470) | 6470..7351 | - | 882 | WP_262556618.1 | ISL3 family transposase | - |
| MUA41_RS12975 (7454) | 7454..7542 | - | 89 | Protein_10 | IS6 family transposase | - |
| MUA41_RS12980 (7599) | 7599..8273 | + | 675 | WP_262556596.1 | IS6 family transposase | - |
| MUA41_RS12985 (8335) | 8335..8724 | - | 390 | WP_262556597.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| MUA41_RS12990 (8742) | 8742..8987 | - | 246 | WP_262556598.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| MUA41_RS12995 (9181) | 9181..9276 | + | 96 | WP_262556599.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
| - (9304) | 9304..9340 | - | 37 | NuclAT_0 | - | Antitoxin |
| - (9304) | 9304..9340 | - | 37 | NuclAT_0 | - | Antitoxin |
| - (9304) | 9304..9340 | - | 37 | NuclAT_0 | - | Antitoxin |
| MUA41_RS13000 (9421) | 9421..9559 | - | 139 | Protein_15 | IS6 family transposase | - |
| MUA41_RS13005 (9748) | 9748..10422 | - | 675 | WP_262556601.1 | IS6 family transposase | - |
| MUA41_RS13010 (10452) | 10452..11291 | - | 840 | WP_262556602.1 | protein rep | - |
| MUA41_RS13015 (11784) | 11784..12329 | - | 546 | WP_262556603.1 | hypothetical protein | - |
| MUA41_RS13020 (12745) | 12745..13173 | - | 429 | WP_262556606.1 | Hsp20/alpha crystallin family protein | - |
| MUA41_RS13025 (13195) | 13195..13362 | - | 168 | WP_195051740.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3592.32 Da Isoelectric Point: 9.7333
>T240018 WP_262556599.1 NZ_CP094703:9181-9276 [Staphylococcus simulans]
MYIIFVHIIAPVISGCAVAYFTYWLSSKRNK
MYIIFVHIIAPVISGCAVAYFTYWLSSKRNK
Download Length: 96 bp
>T240018 NZ_LS483452:c1753007-1752675 [Shewanella benthica]
ATGAAATGTATATTTGTTGAATCAAGAATATTTGAAAAATTCCGTGATAATTACCTCAGTGATGAAGAGTTTAGACTTTT
CCAAGCTGAGCTTATGTCAAACCCAAAGCAGGGTGACGTGATTCAAGGTACAGGTGGTTTGCGAAAGGTTCGAGTTGCAA
GTAAGGGTAAAGGTAAGCGTGGTGGTTCCCGAGTTATCTATTACTTCCTTGATGAAAAGCGACGTTGCTATTTGCTCACA
ATTTATGGAAAGAGCGAAATGTCTGATTTAACCGCAGATCAAAAGAAACAGTTAAAGGCTTTTATGGAGGTATGGCGCAA
TGAGCAATCGTGA
ATGAAATGTATATTTGTTGAATCAAGAATATTTGAAAAATTCCGTGATAATTACCTCAGTGATGAAGAGTTTAGACTTTT
CCAAGCTGAGCTTATGTCAAACCCAAAGCAGGGTGACGTGATTCAAGGTACAGGTGGTTTGCGAAAGGTTCGAGTTGCAA
GTAAGGGTAAAGGTAAGCGTGGTGGTTCCCGAGTTATCTATTACTTCCTTGATGAAAAGCGACGTTGCTATTTGCTCACA
ATTTATGGAAAGAGCGAAATGTCTGATTTAACCGCAGATCAAAAGAAACAGTTAAAGGCTTTTATGGAGGTATGGCGCAA
TGAGCAATCGTGA
Antitoxin
Download Length: 37 bp
>AT240018 NZ_CP094703:c9340-9304 [Staphylococcus simulans]
ATGCACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
ATGCACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
