Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2835218..2835803 Replicon chromosome
Accession NZ_CP094620
Organism Acinetobacter sp. NyZ410

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MTO68_RS13370 Protein ID WP_244012845.1
Coordinates 2835483..2835803 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MTO68_RS13365 Protein ID WP_096734348.1
Coordinates 2835218..2835490 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MTO68_RS13350 (MTO68_13350) 2830517..2831137 - 621 WP_004719624.1 2OG-Fe(II) oxygenase -
MTO68_RS13355 (MTO68_13355) 2831328..2833490 - 2163 WP_004822212.1 malate synthase G -
MTO68_RS13360 (MTO68_13360) 2834130..2834723 - 594 WP_004719619.1 nitroreductase family protein -
MTO68_RS13365 (MTO68_13365) 2835218..2835490 - 273 WP_096734348.1 NadS family protein Antitoxin
MTO68_RS13370 (MTO68_13370) 2835483..2835803 - 321 WP_244012845.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MTO68_RS13375 (MTO68_13375) 2836055..2837299 - 1245 WP_034611715.1 transposase -
MTO68_RS13380 (MTO68_13380) 2837563..2838669 - 1107 WP_004719613.1 signal recognition particle-docking protein FtsY -
MTO68_RS13385 (MTO68_13385) 2838846..2840240 + 1395 WP_056511802.1 pitrilysin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(35-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-84)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12125.92 Da        Isoelectric Point: 8.0125

>T239963 WP_244012845.1 NZ_CP094620:c2835803-2835483 [Acinetobacter sp. NyZ410]
MLFIETSIFTKQIKDLVTDDEYRQLQQNLLVQPDKGDIVKNGGGIRKVRCAQGDKGKSGGIRVIYYWVSEDDHIFFLVAY
PKSVKDNLTDKETAILRQLVKEQLHG

Download         Length: 321 bp

>T239963 NZ_LS483422:744331-744612 [Providencia heimbachae]
GTGATAAAAAGTTTTAAGCACAAAGGAATAGAGCGGTTTTTTAAAACGGGAATAACATCGGGTATTCAAGTAAAGCATAT
AACTAAACTACGGATACAGTTAACGGCGCTGAATACGGCTAAAAAACCTAACGACATGTCTGCGCCGAGTTGGAAGTTAC
ATCAATTAAAGGGTGCTGATTTACAAAATCATTGGTCAATATCCGTAAATGGAAATTGGCGGTTAACGTTTAAATTTGAG
GGTGAGAATGTCATTCTCGTCGACTACCAAGATTATCATTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10209.57 Da        Isoelectric Point: 6.4682

>AT239963 WP_096734348.1 NZ_CP094620:c2835490-2835218 [Acinetobacter sp. NyZ410]
MDNNLFDDLVSSIKEAGEIKRQEIQASRVTELELPDIKAVREKTGLSQNEFAARLHISPRTLQNWEQGRRYPTGPAATLI
RILDTHPSLI

Download         Length: 273 bp

>AT239963 NZ_LS483422:744623-744901 [Providencia heimbachae]
ATGAGCAAAATGCATAATCCAGAGCATCCAGGTTTAGTATTACGCGAATATTTAGATGGTATTTCTGTCACTGACGCAGC
AAAAGCATTGGGTGTGACTCGAGCTACTTTATCTCGAATTTTGAATGGAAATAGTGGAATTTCAGCGGATATGGCATTAA
GGCTTGAAATTGCGCTAGGGACGAGTGCAGAAATGTGGGTTAATATGCAAGCCCAGTATGAATTATGGCAAGCAGCCCAA
GGTACAAGGCCTGTTGTAAAGGCAATCTTTGCGCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References