Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 2835218..2835803 Replicon chromosome
Accession NZ_CP094620
Organism Acinetobacter sp. NyZ410

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag MTO68_RS13370 Protein ID WP_244012845.1
Coordinates 2835483..2835803 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag MTO68_RS13365 Protein ID WP_096734348.1
Coordinates 2835218..2835490 (-) Length 91 a.a.

Genomic Context


MTO68_RS13385MTO68_RS13350MTO68_RS13355MTO68_RS13360MTO68_RS13365MTO68_RS13370MTO68_RS13375MTO68_RS13380
Location: 2838846..2840240 (1395 bp)
Type: Others
Protein ID: WP_056511802.1
Location: 2830517..2831137 (621 bp)
Type: Others
Protein ID: WP_004719624.1
Location: 2831328..2833490 (2163 bp)
Type: Others
Protein ID: WP_004822212.1
Location: 2834130..2834723 (594 bp)
Type: Others
Protein ID: WP_004719619.1
Location: 2835218..2835490 (273 bp)
Type: Antitoxin
Protein ID: WP_096734348.1
Location: 2835483..2835803 (321 bp)
Type: Toxin
Protein ID: WP_244012845.1
Location: 2836055..2837299 (1245 bp)
Type: Others
Protein ID: WP_034611715.1
Location: 2837563..2838669 (1107 bp)
Type: Others
Protein ID: WP_004719613.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MTO68_RS13350 (MTO68_13350)2830517..2831137-621WP_004719624.12OG-Fe(II) oxygenase-
MTO68_RS13355 (MTO68_13355)2831328..2833490-2163WP_004822212.1malate synthase G-
MTO68_RS13360 (MTO68_13360)2834130..2834723-594WP_004719619.1nitroreductase family protein-
MTO68_RS13365 (MTO68_13365)2835218..2835490-273WP_096734348.1NadS family proteinAntitoxin
MTO68_RS13370 (MTO68_13370)2835483..2835803-321WP_244012845.1type II toxin-antitoxin system RelE/ParE family toxinToxin
MTO68_RS13375 (MTO68_13375)2836055..2837299-1245WP_034611715.1transposase-
MTO68_RS13380 (MTO68_13380)2837563..2838669-1107WP_004719613.1signal recognition particle-docking protein FtsY-
MTO68_RS13385 (MTO68_13385)2838846..2840240+1395WP_056511802.1pitrilysin family protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(35-102)

Antitoxin

(37-84)


Sequences


Toxin        


Download         Length: 107 a.a.        Molecular weight: 12125.92 Da        Isoelectric Point: 8.0125

>T239963 WP_244012845.1 NZ_CP094620:c2835803-2835483 [Acinetobacter sp. NyZ410]
MLFIETSIFTKQIKDLVTDDEYRQLQQNLLVQPDKGDIVKNGGGIRKVRCAQGDKGKSGGIRVIYYWVSEDDHIFFLVAY
PKSVKDNLTDKETAILRQLVKEQLHG

Download         Length: 321 bp

>T239963 NZ_LS483422:744331-744612 [Providencia heimbachae]
GTGATAAAAAGTTTTAAGCACAAAGGAATAGAGCGGTTTTTTAAAACGGGAATAACATCGGGTATTCAAGTAAAGCATAT
AACTAAACTACGGATACAGTTAACGGCGCTGAATACGGCTAAAAAACCTAACGACATGTCTGCGCCGAGTTGGAAGTTAC
ATCAATTAAAGGGTGCTGATTTACAAAATCATTGGTCAATATCCGTAAATGGAAATTGGCGGTTAACGTTTAAATTTGAG
GGTGAGAATGTCATTCTCGTCGACTACCAAGATTATCATTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10209.57 Da        Isoelectric Point: 6.4682

>AT239963 WP_096734348.1 NZ_CP094620:c2835490-2835218 [Acinetobacter sp. NyZ410]
MDNNLFDDLVSSIKEAGEIKRQEIQASRVTELELPDIKAVREKTGLSQNEFAARLHISPRTLQNWEQGRRYPTGPAATLI
RILDTHPSLI

Download         Length: 273 bp

>AT239963 NZ_LS483422:744623-744901 [Providencia heimbachae]
ATGAGCAAAATGCATAATCCAGAGCATCCAGGTTTAGTATTACGCGAATATTTAGATGGTATTTCTGTCACTGACGCAGC
AAAAGCATTGGGTGTGACTCGAGCTACTTTATCTCGAATTTTGAATGGAAATAGTGGAATTTCAGCGGATATGGCATTAA
GGCTTGAAATTGCGCTAGGGACGAGTGCAGAAATGTGGGTTAATATGCAAGCCCAGTATGAATTATGGCAAGCAGCCCAA
GGTACAAGGCCTGTTGTAAAGGCAATCTTTGCGCACTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References