Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
| Location | 3208436..3209142 | Replicon | chromosome |
| Accession | NZ_CP094346 | ||
| Organism | [Acidovorax] ebreus strain LS1 | ||
Toxin (Protein)
| Gene name | mqsR | Uniprot ID | - |
| Locus tag | MRB47_RS14975 | Protein ID | WP_252101095.1 |
| Coordinates | 3208436..3208738 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | mqsA | Uniprot ID | - |
| Locus tag | MRB47_RS14980 | Protein ID | WP_252101096.1 |
| Coordinates | 3208741..3209142 (+) | Length | 134 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MRB47_RS14950 (MRB47_14950) | 3204487..3204699 | + | 213 | WP_252101093.1 | hypothetical protein | - |
| MRB47_RS14955 (MRB47_14955) | 3204764..3205501 | - | 738 | WP_011805003.1 | IS21-like element helper ATPase IstB | - |
| MRB47_RS14960 (MRB47_14960) | 3205538..3207082 | - | 1545 | WP_252100662.1 | IS21 family transposase | - |
| MRB47_RS14965 (MRB47_14965) | 3207385..3207906 | + | 522 | WP_252101094.1 | hypothetical protein | - |
| MRB47_RS14970 (MRB47_14970) | 3207903..3208289 | + | 387 | WP_015913139.1 | hypothetical protein | - |
| MRB47_RS14975 (MRB47_14975) | 3208436..3208738 | + | 303 | WP_252101095.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
| MRB47_RS14980 (MRB47_14980) | 3208741..3209142 | + | 402 | WP_252101096.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
| MRB47_RS14985 (MRB47_14985) | 3209165..3210169 | - | 1005 | WP_252101097.1 | site-specific integrase | - |
| MRB47_RS14990 (MRB47_14990) | 3210454..3210756 | + | 303 | WP_252101098.1 | hypothetical protein | - |
| MRB47_RS15000 (MRB47_15000) | 3211444..3213366 | - | 1923 | WP_135149264.1 | SurA N-terminal domain-containing protein | - |
| MRB47_RS15010 (MRB47_15010) | 3213516..3213788 | - | 273 | WP_011805814.1 | HU family DNA-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 10924.59 Da Isoelectric Point: 7.8783
>T239758 WP_252101095.1 NZ_CP094346:3208436-3208738 [[Acidovorax] ebreus]
MEKGTPHCKLPAIRALVEAGQVRATASAYNGARELGINDLAGMCSVVLALSPGNFYKSMTTHADHRVWQDVYRTKTASGN
EVYLKLTVIDDVLIVSFKEL
MEKGTPHCKLPAIRALVEAGQVRATASAYNGARELGINDLAGMCSVVLALSPGNFYKSMTTHADHRVWQDVYRTKTASGN
EVYLKLTVIDDVLIVSFKEL
Download Length: 303 bp
>T239758 NZ_LS483314:c2460436-2460329 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14913.10 Da Isoelectric Point: 7.1653
>AT239758 WP_252101096.1 NZ_CP094346:3208741-3209142 [[Acidovorax] ebreus]
MRCPCCGAAELIHDTRDMPYTYKGEATVIPAVTGEFCPACGEVVLNREHGDRYSELIGLFQRQVNAAYVDPDYIAKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLALVKLFKLLDRHPDLLNELRTA
MRCPCCGAAELIHDTRDMPYTYKGEATVIPAVTGEFCPACGEVVLNREHGDRYSELIGLFQRQVNAAYVDPDYIAKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLALVKLFKLLDRHPDLLNELRTA
Download Length: 402 bp
>AT239758 NZ_LS483314:2460252-2460312 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|