Detailed information of TA system TA239142

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 410551..410746
• Replicon: chromosome
• Accession: NZ_CP093957
• Organism: Enterococcus faecalis strain NY13321

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: MPM64_RS01935
• Protein ID: WP_015543884.1
• Coordinates: 410551..410646 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	410681..410746 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MPM64_RS01915	405730..406845	+	1116	WP_226013756.1	FAD-dependent oxidoreductase	-
MPM64_RS01920	406912..408066	-	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
MPM64_RS01925	408081..408518	-	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
MPM64_RS01930	408533..410305	-	1773	WP_010717458.1	PTS mannitol-specific transporter subunit IIBC	-
MPM64_RS01935	410551..410646	+	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	410681..410746	-	66	-	-	Antitoxin
MPM64_RS01940	410904..411338	-	435	WP_002355276.1	PTS sugar transporter subunit IIA	-
MPM64_RS01945	411349..413382	-	2034	WP_002370205.1	PRD domain-containing protein	-
MPM64_RS01950	413373..415115	-	1743	WP_002403026.1	PTS transporter subunit EIIC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T239142 WP_015543884.1 NZ_CP093957:410551-410646 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T239142 NZ_LR890616:354973-355320 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATGCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTGCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGGCGATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA

Antitoxin

Nucleotide

• Length: 66 bp

>AT239142 NZ_CP093957:c410746-410681 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin