Detailed information of TA system TA239116

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2241054..2241270
• Replicon: chromosome
• Accession: NZ_CP093935
• Organism: Staphylococcus aureus strain WA121-2021_16354

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MQP46_RS11280
• Protein ID: WP_221916266.1
• Coordinates: 2241166..2241270 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2241054..2241109 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MQP46_RS11255	2237260..2237925	-	666	WP_103150216.1	SDR family oxidoreductase	-
MQP46_RS11260	2238077..2238397	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MQP46_RS11265	2238399..2239376	+	978	WP_000019734.1	CDF family zinc efflux transporter CzrB	-
MQP46_RS11270	2239642..2240733	+	1092	WP_000495669.1	hypothetical protein	-
-	2241054..2241109	+	56	-	-	Antitoxin
MQP46_RS11280	2241166..2241270	-	105	WP_221916266.1	hypothetical protein	Toxin
MQP46_RS11285	2241950..2242108	+	159	WP_001792784.1	hypothetical protein	-
MQP46_RS11290	2242766..2243623	-	858	WP_000370925.1	Cof-type HAD-IIB family hydrolase	-
MQP46_RS11295	2243691..2244473	-	783	WP_000908182.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3888.74 Da
• Isoelectric Point: 5.5724

>T239116 WP_221916266.1 NZ_CP093935:c2241270-2241166 [Staphylococcus aureus]
MLLLERTSMSDFEMLIVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T239116 NZ_LR890606:782088-782384 [Escherichia coli]
ATGGAAAAACGCACACCACATACACGTTTGAGTCAGGTTAAAAAACTTGTCAATGCCGGGCAAGTTCGTACAACACGTAG
TGCCCTGTTAAATGCAGATGAGTTAGGTTTGGATTTTGATGGTATGTGTAATGTTATCATTGGATTATCAGAGAGCGACT
TTTATAAAAGCATGACCACCTACTCTGATCATACTATCTGGCAGGATGTTTACAGACCCAGGCTTGTTACAGGCCAGGTT
TATCTTAAAATTACGGTAATTCATGACGTACTGATCGTCTCGTTTAAGGAGAAGTAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT239116 NZ_CP093935:2241054-2241109 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin