Detailed information of TA system TA239097

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2236726..2236942
• Replicon: chromosome
• Accession: NZ_CP093933
• Organism: Staphylococcus aureus strain WA121-2021_15363

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MQP45_RS11270
• Protein ID: WP_221916266.1
• Coordinates: 2236838..2236942 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2236726..2236781 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MQP45_RS11245	2232932..2233597	-	666	WP_103150216.1	SDR family oxidoreductase	-
MQP45_RS11250	2233749..2234069	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MQP45_RS11255	2234071..2235048	+	978	WP_000019734.1	CDF family zinc efflux transporter CzrB	-
MQP45_RS11260	2235314..2236405	+	1092	WP_000495669.1	hypothetical protein	-
-	2236726..2236781	+	56	-	-	Antitoxin
MQP45_RS11270	2236838..2236942	-	105	WP_221916266.1	hypothetical protein	Toxin
MQP45_RS11275	2237459..2237629	+	171	WP_001792292.1	transposase	-
MQP45_RS11280	2237622..2237780	+	159	WP_001792784.1	hypothetical protein	-
MQP45_RS11285	2238438..2239295	-	858	WP_000370925.1	Cof-type HAD-IIB family hydrolase	-
MQP45_RS11290	2239363..2240145	-	783	WP_000908182.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3888.74 Da
• Isoelectric Point: 5.5724

>T239097 WP_221916266.1 NZ_CP093933:c2236942-2236838 [Staphylococcus aureus]
MLLLERTSMSDFEMLIVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T239097 NZ_LR890603:c2472675-2472499 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATAGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT239097 NZ_CP093933:2236726-2236781 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin