Detailed information of TA system TA239078

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2237755..2237971
• Replicon: chromosome
• Accession: NZ_CP093930
• Organism: Staphylococcus aureus strain WA121-2010_15611

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: MPM52_RS11270
• Protein ID: WP_221916266.1
• Coordinates: 2237867..2237971 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	2237755..2237810 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MPM52_RS11245	2233961..2234626	-	666	WP_103150216.1	SDR family oxidoreductase	-
MPM52_RS11250	2234778..2235098	+	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MPM52_RS11255	2235100..2236077	+	978	WP_000019734.1	CDF family zinc efflux transporter CzrB	-
MPM52_RS11260	2236343..2237434	+	1092	WP_000495669.1	hypothetical protein	-
-	2237755..2237810	+	56	-	-	Antitoxin
MPM52_RS11270	2237867..2237971	-	105	WP_221916266.1	hypothetical protein	Toxin
MPM52_RS11275	2238651..2238809	+	159	WP_001792784.1	hypothetical protein	-
MPM52_RS11280	2239467..2240324	-	858	WP_000370925.1	Cof-type HAD-IIB family hydrolase	-
MPM52_RS11285	2240392..2241174	-	783	WP_000908182.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3888.74 Da
• Isoelectric Point: 5.5724

>T239078 WP_221916266.1 NZ_CP093930:c2237971-2237867 [Staphylococcus aureus]
MLLLERTSMSDFEMLIVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T239078 NZ_LR890600:c4659367-4658834 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGTATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Nucleotide

• Length: 56 bp

>AT239078 NZ_CP093930:2237755-2237810 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Structures

Antitoxin