Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | hok-sok/- |
| Location | 39716..39980 | Replicon | plasmid unnamed1 |
| Accession | NZ_CP093549 | ||
| Organism | Escherichia coli strain YL03 | ||
Toxin (Protein)
| Gene name | pndA | Uniprot ID | U9Z417 |
| Locus tag | MPJ80_RS24760 | Protein ID | WP_001387489.1 |
| Coordinates | 39828..39980 (+) | Length | 51 a.a. |
Antitoxin (RNA)
| Gene name | pndB | ||
| Locus tag | - | ||
| Coordinates | 39716..39776 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MPJ80_RS24745 (35818) | 35818..36888 | - | 1071 | WP_012783932.1 | IncI1-type conjugal transfer protein TrbB | - |
| MPJ80_RS24750 (36907) | 36907..38115 | - | 1209 | WP_001703845.1 | IncI1-type conjugal transfer protein TrbA | - |
| - (38295) | 38295..38352 | - | 58 | NuclAT_1 | - | - |
| - (38295) | 38295..38352 | - | 58 | NuclAT_1 | - | - |
| - (38295) | 38295..38352 | - | 58 | NuclAT_1 | - | - |
| - (38295) | 38295..38352 | - | 58 | NuclAT_1 | - | - |
| MPJ80_RS24755 (38422) | 38422..39507 | - | 1086 | WP_000080543.1 | protein finQ | - |
| - (39716) | 39716..39776 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (39716) | 39716..39776 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (39716) | 39716..39776 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (39716) | 39716..39776 | - | 61 | NuclAT_0 | - | Antitoxin |
| MPJ80_RS24760 (39828) | 39828..39980 | + | 153 | WP_001387489.1 | Hok/Gef family protein | Toxin |
| MPJ80_RS24765 (40052) | 40052..40303 | - | 252 | WP_001291964.1 | hypothetical protein | - |
| MPJ80_RS24770 (40804) | 40804..40899 | + | 96 | WP_000609148.1 | DinQ-like type I toxin DqlB | - |
| MPJ80_RS24775 (40964) | 40964..41140 | - | 177 | WP_001054900.1 | hypothetical protein | - |
| MPJ80_RS24780 (41532) | 41532..41741 | + | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
| MPJ80_RS24785 (41813) | 41813..42475 | - | 663 | WP_012783935.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| MPJ80_RS24790 (42546) | 42546..44714 | - | 2169 | WP_058649949.1 | DotA/TraY family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | - | - | 1..89988 | 89988 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5761.10 Da Isoelectric Point: 8.7948
>T238888 WP_001387489.1 NZ_CP093549:39828-39980 [Escherichia coli]
MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
Download Length: 153 bp
>T238888 NZ_LR890524:c2282418-2282086 [Burkholderia cepacia]
ATGAAGAACTGGACGATCCTGTACTACGACGAGCGTGTGAAGCGTGATGTGTTTGCGTTGCCTAAGGGCATTCTTGCGAG
CTACCTCCGTCTGATCGAAACCATGGAGGAACACGGTGCCGATCTACGGATGCCACATTCGCGCGCAATGGGGGCAGGAT
TGTTTGAATTGCGCCCGCGAGGTCGTGAAGGTATCGGACGTGTGTTTTATTGCGTACAGGTTCGATACGAACTCGTCATC
CTGCATTCGTTCGTCAAGAAGACGCAGGAAACGCCTGAAGACGAATTGCGTATCGCCCGTCGGCGAATGAAGGAGGTACA
AAGTAATGGCTAA
ATGAAGAACTGGACGATCCTGTACTACGACGAGCGTGTGAAGCGTGATGTGTTTGCGTTGCCTAAGGGCATTCTTGCGAG
CTACCTCCGTCTGATCGAAACCATGGAGGAACACGGTGCCGATCTACGGATGCCACATTCGCGCGCAATGGGGGCAGGAT
TGTTTGAATTGCGCCCGCGAGGTCGTGAAGGTATCGGACGTGTGTTTTATTGCGTACAGGTTCGATACGAACTCGTCATC
CTGCATTCGTTCGTCAAGAAGACGCAGGAAACGCCTGAAGACGAATTGCGTATCGCCCGTCGGCGAATGAAGGAGGTACA
AAGTAATGGCTAA
Antitoxin
Download Length: 61 bp
>AT238888 NZ_CP093549:c39776-39716 [Escherichia coli]
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
