238847

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 20315..20476 Replicon plasmid unnamed2
Accession NZ_CP093541
Organism Staphylococcus hominis strain C5

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag MOV58_RS12290 Protein ID WP_002441941.1
Coordinates 20315..20410 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 20439..20476 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOV58_RS12260 (16067) 16067..16246 + 180 WP_145418343.1 hypothetical protein -
MOV58_RS12265 (16372) 16372..16563 + 192 WP_002449162.1 hypothetical protein -
MOV58_RS12270 (17394) 17394..17960 - 567 WP_242413996.1 helix-turn-helix transcriptional regulator -
MOV58_RS12275 (18262) 18262..18888 - 627 WP_242413997.1 type II CAAX endopeptidase family protein -
MOV58_RS12280 (19074) 19074..19253 + 180 Protein_22 hypothetical protein -
MOV58_RS12285 (19357) 19357..19968 - 612 WP_242413998.1 type II CAAX endopeptidase family protein -
MOV58_RS12290 (20315) 20315..20410 + 96 WP_002441941.1 type I toxin-antitoxin system Fst family toxin Toxin
- (20439) 20439..20476 - 38 NuclAT_0 - Antitoxin
- (20439) 20439..20476 - 38 NuclAT_0 - Antitoxin
- (20439) 20439..20476 - 38 NuclAT_0 - Antitoxin
MOV58_RS12295 (20589) 20589..21362 + 774 WP_242413999.1 hypothetical protein -
MOV58_RS12300 (21397) 21397..22398 + 1002 WP_242414000.1 nucleotidyltransferase -
MOV58_RS12305 (22558) 22558..23166 + 609 WP_242414001.1 recombinase family protein -
MOV58_RS12310 (24391) 24391..25164 - 774 WP_077701580.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3560.34 Da        Isoelectric Point: 9.9256

>T238847 WP_002441941.1 NZ_CP093541:20315-20410 [Staphylococcus hominis]
MLMIFVHIIAPVISGCAVAYFTYWLSSKRNK

Download         Length: 96 bp

>T238847 NZ_LR890508:c762532-762356 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 38 bp

>AT238847 NZ_CP093541:c20476-20439 [Staphylococcus hominis]
TATGCACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References