Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 20902..21435 Replicon plasmid p5
Accession NZ_CP093533
Organism Shinella zoogloeoides strain XJ20

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag MOE34_RS25245 Protein ID WP_242225307.1
Coordinates 21163..21435 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag MOE34_RS25240 Protein ID WP_242225315.1
Coordinates 20902..21162 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MOE34_RS25210 16629..17195 + 567 WP_242225297.1 recombinase family protein -
MOE34_RS25215 17607..17816 + 210 WP_242225299.1 ribbon-helix-helix protein, CopG family -
MOE34_RS25220 18011..18886 + 876 WP_242225301.1 helix-turn-helix domain-containing protein -
MOE34_RS25225 19122..19778 + 657 WP_242225302.1 SprT-like domain-containing protein -
MOE34_RS25230 19853..20512 + 660 WP_242225304.1 AAA family ATPase -
MOE34_RS25235 20509..20847 + 339 WP_242225305.1 chromosome partitioning protein ParB -
MOE34_RS25240 20902..21162 + 261 WP_242225315.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MOE34_RS25245 21163..21435 + 273 WP_242225307.1 type II toxin-antitoxin system YafQ family toxin Toxin
MOE34_RS25250 21486..21725 + 240 WP_242225309.1 hypothetical protein -
MOE34_RS25255 22027..23697 - 1671 WP_242225318.1 type IV secretory system conjugative DNA transfer family protein -
MOE34_RS25260 23790..24071 - 282 WP_242225310.1 mobilization protein -
MOE34_RS25265 24086..24862 - 777 WP_242225320.1 NYN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..25056 25056


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-83)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10682.18 Da        Isoelectric Point: 9.9463

>T238837 WP_242225307.1 NZ_CP093533:21163-21435 [Shinella zoogloeoides]
VRDPSYSGQFRRDVKRAEKRGKDMAKLRHVLQLLIEEAPLPARLRDHPLKSNWIGYRDLHIESDWLLIYKVDATSVHFER
TGTHSDLFRE

Download         Length: 273 bp

>T238837 NZ_LR890500:5081733-5082050 [Klebsiella pneumoniae]
ATGTTCAGATTGGTTGTGCATGTGGACGTTAAAAAGGAATTGCAGGCGCTTCCGCCCATTGTCCAGGCGAAGATGATCCG
GCAATTAGACAAGTTACGCCAAAATCCCACCGCGCTGAGAGAACCTGACAGTAAACCGCTGGGGCAGGGGCTATTTGAAA
TTCGTGCGTTAGGTTCGGTACAGGGGCGAGGGATCTACGTTTTTCAGCAAGGCAAGACGCTCTTTCTGCTACGGGTTTTT
GTCAAGAAAACGCAAAAAACCCCGTCATCGGAAATTCGCCTGGCGCTGAAGCGATTAGAGGAGATGCGCAATGAGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9341.84 Da        Isoelectric Point: 9.7655

>AT238837 WP_242225315.1 NZ_CP093533:20902-21162 [Shinella zoogloeoides]
MRVDSVVRARVDAETKDSATKALAEMGLSVSDYIRMALVRVARDKAIPFPVKVPNAETIAAMEKTARGEDVHKAKDAGDL
FKQLGI

Download         Length: 261 bp

>AT238837 NZ_LR890500:5082043-5082330 [Klebsiella pneumoniae]
ATGAGTAAAAAGATCATTGACTGGGATACGTTAAAAACAGAACTGCTTGGCCAGCCTGAGGTTCAGGCTGCATTCGATGC
GCAAGAACGTCAACAGCGATTACGTACTATGCTGGCGCAATGGCGCGAGCAGGCGGGGCTAACCCGAGCCCAGGTGGCGC
AGAGGATGGGGGTGAGTGCGCCGACGGTCTCCAGAATGGAAGCCAATATCACCCGCGCCAGTCTGGATACCTTAACGCGA
TACGCGTTAGCCTGCGGTATAAAGCACCCGCAAGTTTTACTTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References