Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3586497..3586719 Replicon chromosome
Accession NC_012759
Organism Escherichia coli BW2952

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag BWG_RS22845 Protein ID WP_000141634.1
Coordinates 3586497..3586604 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3586653..3586719 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWG_RS17785 3581750..3582502 - 753 Protein_3388 cellulose biosynthesis protein BcsQ -
BWG_RS17790 (BWG_3223) 3582514..3582702 - 189 WP_001063318.1 YhjR family protein -
BWG_RS17795 (BWG_3224) 3582975..3584546 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
BWG_RS17800 (BWG_3225) 3584543..3584734 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
BWG_RS17805 (BWG_3226) 3584731..3586410 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
BWG_RS22845 (BWG_3227) 3586497..3586604 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 3586653..3586719 + 67 - - Antitoxin
BWG_RS17820 (BWG_3228) 3587080..3588351 + 1272 WP_001295225.1 transporter -
BWG_RS17825 (BWG_3229) 3588381..3589385 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
BWG_RS17830 (BWG_3230) 3589382..3590365 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
BWG_RS17835 (BWG_3231) 3590376..3591278 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T23872 WP_000141634.1 NC_012759:c3586604-3586497 [Escherichia coli BW2952]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T23872 NC_012759:c3586604-3586497 [Escherichia coli BW2952]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT23872 NC_012759:3586653-3586719 [Escherichia coli BW2952]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References