Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 1157647..1157869 Replicon chromosome
Accession NC_012759
Organism Escherichia coli BW2952

Toxin (Protein)


Gene name ldrD Uniprot ID J7R083
Locus tag BWG_RS05770 Protein ID WP_000170963.1
Coordinates 1157647..1157754 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 1157802..1157869 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWG_RS05740 (BWG_1036) 1152956..1154038 + 1083 WP_000804726.1 peptide chain release factor 1 -
BWG_RS05745 (BWG_1037) 1154038..1154871 + 834 WP_000456467.1 peptide chain release factor N(5)-glutamine methyltransferase -
BWG_RS05750 (BWG_1038) 1154868..1155260 + 393 WP_000200374.1 invasion regulator SirB2 -
BWG_RS05755 (BWG_1039) 1155264..1156073 + 810 WP_001257044.1 invasion regulator SirB1 -
BWG_RS05760 (BWG_1040) 1156109..1156963 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
BWG_RS05765 (BWG_1041) 1157112..1157219 - 108 WP_000170955.1 small toxic polypeptide LdrA/LdrC -
BWG_RS05770 (BWG_1042) 1157647..1157754 - 108 WP_000170963.1 small toxic polypeptide LdrB Toxin
- 1157802..1157869 + 68 - - Antitoxin
BWG_RS05775 (BWG_1043) 1158182..1158289 - 108 WP_000170955.1 small toxic polypeptide LdrA/LdrC -
BWG_RS05780 (BWG_1044) 1158693..1159793 - 1101 WP_000063607.1 sodium-potassium/proton antiporter ChaA -
BWG_RS05785 (BWG_1045) 1160063..1160293 + 231 WP_001146444.1 putative cation transport regulator ChaB -
BWG_RS05790 (BWG_1046) 1160451..1161146 + 696 WP_001336325.1 glutathione-specific gamma-glutamylcyclotransferase -
BWG_RS05795 (BWG_1047) 1161190..1161543 - 354 WP_001169669.1 DsrE/F sulfur relay family protein YchN -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3971.74 Da        Isoelectric Point: 11.4779

>T23842 WP_000170963.1 NC_012759:c1157754-1157647 [Escherichia coli BW2952]
MTLAQFAMTFWHDLAAPILAGIITAAIVGWWRNRK

Download         Length: 108 bp

>T23842 NC_012759:c1157754-1157647 [Escherichia coli BW2952]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 68 bp

>AT23842 NC_012759:1157802-1157869 [Escherichia coli BW2952]
GTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References