Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-RelB |
| Location | 59287..59795 | Replicon | plasmid p1 |
| Accession | NZ_CP093329 | ||
| Organism | Rahnella aceris strain S2-A69 | ||
Toxin (Protein)
| Gene name | yoeB | Uniprot ID | H8P157 |
| Locus tag | MNO10_RS22060 | Protein ID | WP_013578404.1 |
| Coordinates | 59287..59553 (-) | Length | 89 a.a. |
Antitoxin (Protein)
| Gene name | yefM | Uniprot ID | H8P156 |
| Locus tag | MNO10_RS22065 | Protein ID | WP_013578405.1 |
| Coordinates | 59550..59795 (-) | Length | 82 a.a. |
Genomic Context
Location: 54923..57022 (2100 bp)
Type: Others
Protein ID: WP_013578365.1
Type: Others
Protein ID: WP_013578365.1
Location: 60105..61154 (1050 bp)
Type: Others
Protein ID: WP_014683046.1
Type: Others
Protein ID: WP_014683046.1
Location: 62134..62475 (342 bp)
Type: Others
Protein ID: WP_241917281.1
Type: Others
Protein ID: WP_241917281.1
Location: 62823..64283 (1461 bp)
Type: Others
Protein ID: WP_014683042.1
Type: Others
Protein ID: WP_014683042.1
Location: 57380..58966 (1587 bp)
Type: Others
Protein ID: WP_013578364.1
Type: Others
Protein ID: WP_013578364.1
Location: 59287..59553 (267 bp)
Type: Toxin
Protein ID: WP_013578404.1
Type: Toxin
Protein ID: WP_013578404.1
Location: 59550..59795 (246 bp)
Type: Antitoxin
Protein ID: WP_013578405.1
Type: Antitoxin
Protein ID: WP_013578405.1
Location: 61246..61725 (480 bp)
Type: Others
Protein ID: WP_014683045.1
Type: Others
Protein ID: WP_014683045.1
Location: 61722..61982 (261 bp)
Type: Others
Protein ID: WP_200227549.1
Type: Others
Protein ID: WP_200227549.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MNO10_RS22050 (MNO10_22050) | 54923..57022 | + | 2100 | WP_013578365.1 | peptidase domain-containing ABC transporter | - |
| MNO10_RS22055 (MNO10_22055) | 57380..58966 | - | 1587 | WP_013578364.1 | sensor domain-containing diguanylate cyclase | - |
| MNO10_RS22060 (MNO10_22060) | 59287..59553 | - | 267 | WP_013578404.1 | Txe/YoeB family addiction module toxin | Toxin |
| MNO10_RS22065 (MNO10_22065) | 59550..59795 | - | 246 | WP_013578405.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| MNO10_RS22070 (MNO10_22070) | 60105..61154 | + | 1050 | WP_014683046.1 | tyrosine-type recombinase/integrase | - |
| MNO10_RS22075 (MNO10_22075) | 61246..61725 | - | 480 | WP_014683045.1 | GNAT family N-acetyltransferase | - |
| MNO10_RS22080 (MNO10_22080) | 61722..61982 | - | 261 | WP_200227549.1 | DUF1778 domain-containing protein | - |
| MNO10_RS22085 (MNO10_22085) | 62134..62475 | + | 342 | WP_241917281.1 | MFS transporter | - |
| MNO10_RS22090 (MNO10_22090) | 62823..64283 | + | 1461 | WP_014683042.1 | sensor domain-containing diguanylate cyclase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..123458 | 123458 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 89 a.a. Molecular weight: 10490.04 Da Isoelectric Point: 10.0392
>T238155 WP_013578404.1 NZ_CP093329:c59553-59287 [Rahnella aceris]
MKTRFTKRGAADYQYWQGSNAKIFERIRILIHAIHADPLGGIGKPERLRHYKNPALYSRRIDREHRLVYSMVNDELTIIA
CRYHYDDV
MKTRFTKRGAADYQYWQGSNAKIFERIRILIHAIHADPLGGIGKPERLRHYKNPALYSRRIDREHRLVYSMVNDELTIIA
CRYHYDDV
Download Length: 267 bp
>T238155 NZ_LR890240:349018-349365 [Klebsiella pneumoniae]
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATTCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTCCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGGCGATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA
ATGTGGGATGTAGAAACGACGGATACGTTTGATACCTGGTTCGAATTACAAAGTAGAGCTTTAAAAGAGGATATGTTGGC
CACGATTCTCATCCTGTCTGAGTTTGCTCCGCAGCTTGGGCGCCCGTATGTTGATACGGTGAAAGATTCAACGTTTCAGA
ATATGAAAGAACTCCGGGTTCAGCATCATGGGCTCCCCATCCGCGCCTTTTTTGCTTTTGATCCTCTGCGGAAAGCTATC
GTTTTATGTGCGGGCGATAAGGATGGCATGAATGAGAAACGTTTTTACAAAGAGATGATTACTCTGGCTGACAGAGAATT
CAGCCAACACCTGACTAAGGAGCGATAA
Antitoxin
Download Length: 82 a.a. Molecular weight: 9027.06 Da Isoelectric Point: 4.1947
>AT238155 WP_013578405.1 NZ_CP093329:c59795-59550 [Rahnella aceris]
MHSLTFTDARKHFAETMQQVSDNAEPVRILRRDAPDVVLIDAAEYDAILETLYLFSNPANAAHINASLAELDRGDTVEIE
V
MHSLTFTDARKHFAETMQQVSDNAEPVRILRRDAPDVVLIDAAEYDAILETLYLFSNPANAAHINASLAELDRGDTVEIE
V
Download Length: 246 bp
>AT238155 NZ_LR890240:349365-349664 [Klebsiella pneumoniae]
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA
ATGGCCACGCTAAAAGAACTCATGGCGAAACAGAGTCCTGATAGCCAGCAGCGTATTGCAGCGAAAGCGGCAGAGATACG
CCAGTCTGTCGCTTTAAACTTGCTTCGAGAAGAGTTGCAAATGTCGCAAACAGAGATGGCTGCGGCTATGGGGGTAAAGC
AGCCAACGATCGCTAAAATGGAACAGGCTGATAACGACCCTCGGCTTTCGACCCTAAAACGCTACATTGCGGCATTGGGG
GGAGAACTCAGTATAAATGTCACATTGCCGACTGGAAAAAAAGTCTCGTTTAATTTGTGA