Detailed information of TA system TA237892

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): symE-sokW/SymE(toxin)
• Location: 732349..732761
• Replicon: chromosome
• Accession: NZ_CP093239
• Organism: Escherichia marmotae strain W49-2

Toxin (Protein)

• Gene name: symE
• Uniprot ID: -
• Locus tag: MNY74_RS03475
• Protein ID: WP_181478973.1
• Coordinates: 732349..732690 (-)
• Length: 114 a.a.

Antitoxin (RNA)

Gene name	sokW
Locus tag	-
Coordinates	732685..732761 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MNY74_RS03455 (728805)	728805..729749	+	945	WP_181478972.1	Rpn family recombination-promoting nuclease/putative transposase	-
MNY74_RS03460 (729985)	729985..730113	+	129	WP_228995449.1	DUF1127 domain-containing protein	-
MNY74_RS03465 (730209)	730209..731088	+	880	Protein_678	DUF262 domain-containing protein	-
MNY74_RS03470 (731139)	731139..732302	+	1164	WP_181479262.1	DUF262 and DUF1524 domain-containing protein	-
MNY74_RS03475 (732349)	732349..732690	-	342	WP_181478973.1	endoribonuclease SymE	Toxin
- (732685)	732685..732761	+	77	NuclAT_10	-	Antitoxin
- (732685)	732685..732761	+	77	NuclAT_10	-	Antitoxin
- (732685)	732685..732761	+	77	NuclAT_10	-	Antitoxin
- (732685)	732685..732761	+	77	NuclAT_10	-	Antitoxin
- (732685)	732685..732761	+	77	NuclAT_11	-	Antitoxin
- (732685)	732685..732761	+	77	NuclAT_11	-	Antitoxin
- (732685)	732685..732761	+	77	NuclAT_11	-	Antitoxin
- (732685)	732685..732761	+	77	NuclAT_11	-	Antitoxin
MNY74_RS03480 (732918)	732918..734267	-	1350	WP_181478974.1	restriction endonuclease subunit S	-
MNY74_RS03485 (734264)	734264..735853	-	1590	WP_105268051.1	type I restriction-modification system methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (20-71)

Sequences

Toxin

Protein

• Length: 114 a.a.
• Molecular weight: 12368.21 Da
• Isoelectric Point: 8.4952

>T237892 WP_181478973.1 NZ_CP093239:c732690-732349 [Escherichia marmotae]
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPNYNRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQLPATEESE
LMQSLRQVCKLSARKQKQVQEFIGVIAGKQKVA

Nucleotide

• Length: 342 bp

>T237892 NZ_LR882997:c4673483-4673310 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Nucleotide

• Length: 77 bp

>AT237892 NZ_CP093239:732685-732761 [Escherichia marmotae]
AGTCATAACTGCTATTCCCTATAAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Structures

Antitoxin