Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2724445..2724963 Replicon chromosome
Accession NZ_CP093217
Organism Staphylococcus edaphicus strain CCM 8731

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag MNY58_RS13425 Protein ID WP_099089794.1
Coordinates 2724445..2724714 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MNY58_RS13430 Protein ID WP_099089795.1
Coordinates 2724715..2724963 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MNY58_RS13410 (MNY58_13405) 2720851..2720994 + 144 WP_099091191.1 FeoB-associated Cys-rich membrane protein -
MNY58_RS13415 (MNY58_13410) 2721108..2722421 + 1314 Protein_2610 IS1182 family transposase -
MNY58_RS13420 (MNY58_13415) 2722774..2724524 + 1751 Protein_2611 IS1182 family transposase -
MNY58_RS13425 (MNY58_13420) 2724445..2724714 - 270 WP_099089794.1 Txe/YoeB family addiction module toxin Toxin
MNY58_RS13430 (MNY58_13425) 2724715..2724963 - 249 WP_099089795.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MNY58_RS13435 (MNY58_13430) 2725712..2726554 - 843 WP_249740133.1 PH domain-containing protein -
MNY58_RS13440 (MNY58_13435) 2727072..2727968 - 897 WP_099089798.1 ABC transporter ATP-binding protein -
MNY58_RS13445 (MNY58_13440) 2727968..2728657 - 690 WP_099089799.1 ABC transporter permease -
MNY58_RS13450 (MNY58_13445) 2728804..2729064 + 261 WP_099089800.1 hypothetical protein -
MNY58_RS13455 (MNY58_13450) 2729192..2729356 + 165 WP_153043316.1 aureocin A53 family class IId bacteriocin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10279.65 Da        Isoelectric Point: 9.7958

>T237814 WP_099089794.1 NZ_CP093217:c2724714-2724445 [Staphylococcus edaphicus]
VAKLNITFSPQAFDDYEYFQTKDGKMVKRINQLLKSISRDGALDGIGKPEKLVGNFSGYYSRRFNHEHRLGYTVNDNAIL
VASCRYHYK

Download         Length: 270 bp

>T237814 NZ_LR882967:c3614737-3614378 [Planktothrix pseudagardhii]
ATGCTGAGTGAACCACCACCTATCCAAATCGCGCTTACTCCCCGCTTCAAAAGGGATCTTCGAGAACTGGCTAAACACTA
TCGTTCAATTCGTACCGATCTCCAACCCTTAATCGAACAACTTCAAGCAGGTGAAATTCCTGGTGATAGAATTGCAGGTA
TTAAATATACCGTTTTTAAAGTTCGTCTTAAAAATAGTAATATCCAAAAAGGAAAAAGTGGGGGCTATCGAGTTATTTAT
TATCTGAAAACAAATCAAGCCATCATTCTTGCTACAATTTATTCCAAATCTGACGACTCAGATATTAGTCATAAAATCAT
TGAAGAGGTGATCACTCAATATGAGAACGAAATTGGTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9541.71 Da        Isoelectric Point: 4.5859

>AT237814 WP_099089795.1 NZ_CP093217:c2724963-2724715 [Staphylococcus edaphicus]
MIVKSYSYVRENFKDMINKVNDDSDTITITTKDRNAVIMSEDNYNEIMETLYLQQNPANAKHLSESIENLERGNVKNKDI
LI

Download         Length: 249 bp

>AT237814 NZ_LR882967:c3614972-3614727 [Planktothrix pseudagardhii]
ATGAAAGCAATTGAAACGACAGCGACTATTAATGAAAGTGGGCAACTAACACTTGATCAATCATTAGGAACCACTAAACC
ACAGCGTGTTCGGGTTATTGTTTTAATTCCTGAAGATGACGAAGTTGATCCCAATGAAACGCCGACTGAAATTCTGATAG
AAGGGATTCGTCAAGGTTTATACGAAGCATTAACGGGACAGACTATTCCGCTCTCAGAAATGTGGGAAGGTATTGATGCT
GAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References