Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2717788..2718121 | Replicon | chromosome |
Accession | NZ_CP092907 | ||
Organism | Enterococcus faecalis strain LJX 0909 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | S4BYM2 |
Locus tag | MK744_RS13090 | Protein ID | WP_002392696.1 |
Coordinates | 2717788..2717931 (+) | Length | 48 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2717905..2718121 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MK744_RS13075 (2714007) | 2714007..2714645 | - | 639 | WP_002375448.1 | lytic polysaccharide monooxygenase | - |
MK744_RS13080 (2715330) | 2715330..2716946 | + | 1617 | WP_085444189.1 | phosphatase PAP2/LCP family protein | - |
MK744_RS13085 (2717161) | 2717161..2717358 | + | 198 | WP_002358966.1 | type I toxin-antitoxin system toxin PepG1 | - |
- (2717291) | 2717291..2717477 | - | 187 | NuclAT_5 | - | - |
- (2717508) | 2717508..2717676 | - | 169 | NuclAT_10 | - | - |
- (2717530) | 2717530..2717676 | - | 147 | NuclAT_8 | - | - |
MK744_RS13090 (2717788) | 2717788..2717931 | + | 144 | WP_002392696.1 | type I toxin-antitoxin system toxin PepG1 | Toxin |
- (2717864) | 2717864..2718119 | - | 256 | NuclAT_4 | - | - |
- (2718071) | 2718071..2718120 | + | 50 | NuclAT_13 | - | - |
- (2717905) | 2717905..2718121 | - | 217 | NuclAT_9 | - | Antitoxin |
MK744_RS13095 (2718121) | 2718121..2721030 | - | 2910 | WP_241408261.1 | WxL domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 48 a.a. Molecular weight: 5297.43 Da Isoelectric Point: 10.6867
>T237386 WP_002392696.1 NZ_CP092907:2717788-2717931 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
Download Length: 144 bp
>T237386 NZ_LR882050:1062411-1062518 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 217 bp
>AT237386 NZ_CP092907:c2718121-2717905 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGATGGTCGTTGTGCTATA
ATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCAATTGTATTATTT
AAAAATAACCGTACTGGTCAAAGTAAACGGTTATTTTTTATTGTCATTTTTAAGCAA
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGATGGTCGTTGTGCTATA
ATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCAATTGTATTATTT
AAAAATAACCGTACTGGTCAAAGTAAACGGTTATTTTTTATTGTCATTTTTAAGCAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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