Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2634584..2634845 | Replicon | chromosome |
Accession | NZ_CP092907 | ||
Organism | Enterococcus faecalis strain LJX 0909 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | S4BYM2 |
Locus tag | MK744_RS12705 | Protein ID | WP_002392696.1 |
Coordinates | 2634702..2634845 (-) | Length | 48 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2634584..2634728 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MK744_RS12690 (2629951) | 2629951..2630664 | - | 714 | WP_002354877.1 | trehalose operon repressor | - |
MK744_RS12695 (2630925) | 2630925..2633669 | + | 2745 | WP_142957073.1 | glycosyl hydrolase family 65 protein | - |
MK744_RS12700 (2633684) | 2633684..2634334 | + | 651 | WP_002419627.1 | beta-phosphoglucomutase | - |
- (2634403) | 2634403..2634542 | + | 140 | NuclAT_12 | - | - |
- (2634584) | 2634584..2634728 | + | 145 | NuclAT_11 | - | Antitoxin |
- (2634584) | 2634584..2634769 | + | 186 | NuclAT_7 | - | - |
MK744_RS12705 (2634702) | 2634702..2634845 | - | 144 | WP_002392696.1 | type I toxin-antitoxin system toxin PepG1 | Toxin |
- (2635010) | 2635010..2635208 | + | 199 | NuclAT_6 | - | - |
MK744_RS12710 (2635141) | 2635141..2635284 | - | 144 | WP_202497224.1 | type I toxin-antitoxin system toxin PepG1 | - |
MK744_RS12715 (2635516) | 2635516..2636487 | - | 972 | WP_002381060.1 | ribose-phosphate diphosphokinase | - |
MK744_RS12720 (2636662) | 2636662..2637099 | - | 438 | WP_002354871.1 | peptide-methionine (R)-S-oxide reductase MsrB | - |
MK744_RS12725 (2637232) | 2637232..2637786 | - | 555 | WP_002354869.1 | Maf family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 48 a.a. Molecular weight: 5297.43 Da Isoelectric Point: 10.6867
>T237365 WP_002392696.1 NZ_CP092907:c2634845-2634702 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK
Download Length: 144 bp
>T237365 NZ_LR881940:c2477121-2476945 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGTTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA
GTGAAACAAAGCGAGTTCAGACGTTGGTTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA
Antitoxin
Download Length: 145 bp
>AT237365 NZ_CP092907:2634584-2634728 [Enterococcus faecalis]
TGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGATT
TAGTTATAAAAAATAACCGTACCAGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAA
TGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACCGATT
TAGTTATAAAAAATAACCGTACCAGTCAAAGTAGACGGTTATTTTTTATTGTCATTTTTAAGCAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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