Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3970251..3970950 Replicon chromosome
Accession NZ_CP092827
Organism Pseudomonas sp. LS.1a

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag MKK04_RS18445 Protein ID WP_241105868.1
Coordinates 3970654..3970950 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag MKK04_RS18440 Protein ID WP_207830085.1
Coordinates 3970251..3970652 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKK04_RS18420 (MKK04_18420) 3965269..3966090 - 822 WP_207830092.1 transporter substrate-binding domain-containing protein -
MKK04_RS18425 (MKK04_18425) 3966279..3967208 - 930 WP_013973453.1 FAD-binding protein -
MKK04_RS18430 (MKK04_18430) 3967209..3967958 - 750 WP_207830090.1 electron transfer flavoprotein subunit beta/FixA family protein -
MKK04_RS18435 (MKK04_18435) 3968497..3970179 + 1683 WP_272493135.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
MKK04_RS18440 (MKK04_18440) 3970251..3970652 - 402 WP_207830085.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
MKK04_RS18445 (MKK04_18445) 3970654..3970950 - 297 WP_241105868.1 type II toxin-antitoxin system MqsR family toxin Toxin
MKK04_RS18450 (MKK04_18450) 3971045..3972370 - 1326 WP_241105869.1 MFS transporter -
MKK04_RS18455 (MKK04_18455) 3972443..3972922 - 480 WP_207830080.1 histidine kinase -
MKK04_RS18460 (MKK04_18460) 3973091..3973567 - 477 WP_207830078.1 sigma-70 family RNA polymerase sigma factor -
MKK04_RS18465 (MKK04_18465) 3974049..3975221 + 1173 WP_241105870.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11139.14 Da        Isoelectric Point: 10.4533

>T237220 WP_241105868.1 NZ_CP092827:c3970950-3970654 [Pseudomonas sp. LS.1a]
MEKRMPHCPLQRVKALLSLGKVRTTGVATQGARALGIEPFAMLNIVRELTPGDFHKSMTTYNNHRVWQDAYRPQTAVGRV
YLKLMVVDDLLIVSFKEL

Download         Length: 297 bp

>T237220 NZ_LR813084:c110853-110431 [Delftia tsuruhatensis]
ATGCAAGAGATTGAGGCCCGGGCGGGCGCATCTTTTCTCGACAGCAATGTCGTGCTCTATCTGCTGTCTGCAGAGAGTGC
AAAAGCCGGCAGCGCCGAGGCACTGCTGAAGACCGGGCCTGTCATCAGCGTGCAGGTGCTCAACGAGGTGACCCATGTCT
GCATACGCAAGCTGCACATGGGCTGGAACGATGTGGAGCAATTTCTGGCACTGGTACGGAGCTTTTGCCGTGTCGTGCCC
TTGACCGAGGACATCCATGATCTGGCGCGGCAGATTGCGCCGCGCAACGGGCTGTCCTTCTATGACGCATGCATCGTGGC
TGCAGCCACCGCCTCAGGCTGCACCACGCTGCACAGCGAGGACATGAACCATGGCCAGGCCATCGGCAGCCTGACCCTCT
GCAACCCGTTCAAGGCCGCATGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14620.85 Da        Isoelectric Point: 4.9661

>AT237220 WP_207830085.1 NZ_CP092827:c3970652-3970251 [Pseudomonas sp. LS.1a]
MKCPLCGGAELVAQSKDMPYRYKGEATVIPDVYGEYCPACGEVILGMGEAQRMSDLMSAFERQVNGAVVDPAFIAAMRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT237220 NZ_LR813084:c111073-110840 [Delftia tsuruhatensis]
ATGCAAGTCTCCAAATGGGGCAACAGCCTGGCCGTCCGGCTGCCGGCCGCCGTCGTGCAGGCGCTGGAACTGCGTGAGGG
CGACGATATCGAGATCACCGTGGAGGGCTCGCGCAGCTTCGCGGTGCGCAAGGCACCAAGTGACGAGGAACGCCTCGAAA
GCCTGCGCGCCTTCCGGGGCAGGCTGCCCGCCGGCTTCCGTTTCAACCGGGACGAGGCCAATGCAAGAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References