Detailed information of TA system TA237211

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2168957..2169155
• Replicon: chromosome
• Accession: NZ_CP092825
• Organism: Staphylococcus aureus strain GY8

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: MK796_RS10695
• Protein ID: WP_001802298.1
• Coordinates: 2169051..2169155 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF
Locus tag	-
Coordinates	2168957..2168995 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MK796_RS10670	2165129..2165794	-	666	WP_001024088.1	SDR family oxidoreductase	-
MK796_RS10675	2165946..2166266	+	321	WP_000139802.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
MK796_RS10680	2166268..2167245	+	978	WP_000019732.1	CDF family zinc efflux transporter CzrB	-
MK796_RS10685	2167511..2168602	+	1092	WP_000495695.1	hypothetical protein	-
MK796_RS10690	2168937..2169011	+	75	Protein_2066	hypothetical protein	-
-	2168957..2168995	+	39	-	-	Antitoxin
MK796_RS10695	2169051..2169155	-	105	WP_001802298.1	hypothetical protein	Toxin
MK796_RS10700	2169316..2169799	-	484	Protein_2068	recombinase family protein	-
MK796_RS10705	2169842..2170978	-	1137	Protein_2069	SAP domain-containing protein	-
MK796_RS10710	2171267..2171359	+	93	WP_031844941.1	hypothetical protein	-
MK796_RS10720	2172054..2172911	-	858	WP_000370919.1	HAD family hydrolase	-
MK796_RS10725	2172979..2173761	-	783	WP_000908190.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T237211 WP_001802298.1 NZ_CP092825:c2169155-2169051 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T237211 NZ_LR792683:3182579-3183016 [Kyrpidia spormannii]
GTGAAATATTTACTGGACACTTGTGTCATTTCTGAACTGGTCAAGAAGGCTCCCGCTCCCGCAGTTCTGCGGTGGGTCGA
GAACCAGGATGAGGAGAACCTGTATTTGAGCGTATTGACCCTGGGAGAACTGCAACGCGGTGTAAGTAAATTGCTGGATC
GCAGTCGTGCAGAACAATTGCAGGCGTGGTTGAATGATGACTTGACCCACCGCTTTCAGAGACGCATCTTGCCTGTCGAC
CAAAAGGTGGCAAAGGCTTGGGGAGAAATCAGTGGAGACGCGGCGCGGCGAGGAGAAACACTCCCTGTCATGGACAGTCT
CATTGCAGCCACCGCCCAGGTTCACGGCCTGGTTGTGGTCACGCGAAACGTACGCGACATAGAACGTTGCCGCGTTCCGG
TTACGAATCCTTGGCCGGACACGCGCGCCGACCTGTAA

Antitoxin

Nucleotide

• Length: 39 bp

>AT237211 NZ_CP092825:2168957-2168995 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin