Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2558134..2558532 Replicon chromosome
Accession NZ_CP092784
Organism Enterococcus sp. LX10

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag MKZ30_RS12050 Protein ID WP_023894767.1
Coordinates 2558134..2558238 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2558390..2558532 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKZ30_RS12035 (2553447) 2553447..2554160 - 714 WP_002354877.1 trehalose operon repressor -
MKZ30_RS12040 (2554421) 2554421..2557165 + 2745 WP_129226010.1 glycosyl hydrolase family 65 protein -
MKZ30_RS12045 (2557180) 2557180..2557830 + 651 WP_016614233.1 beta-phosphoglucomutase -
- (2558014) 2558014..2558201 + 188 NuclAT_4 - -
MKZ30_RS12050 (2558134) 2558134..2558238 - 105 WP_023894767.1 putative holin-like toxin Toxin
- (2558390) 2558390..2558532 + 143 NuclAT_10 - Antitoxin
MKZ30_RS13325 (2558623) 2558623..2558745 - 123 WP_002419628.1 hypothetical protein -
MKZ30_RS12055 (2559538) 2559538..2560509 - 972 WP_002381060.1 ribose-phosphate diphosphokinase -
MKZ30_RS12060 (2560684) 2560684..2561121 - 438 WP_010715474.1 peptide-methionine (R)-S-oxide reductase MsrB -
MKZ30_RS12065 (2561254) 2561254..2561808 - 555 WP_033601100.1 nucleoside triphosphate pyrophosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-34)


Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3799.63 Da        Isoelectric Point: 10.0079

>T237140 WP_023894767.1 NZ_CP092784:c2558238-2558134 [Enterococcus sp. LX10]
MSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Download         Length: 105 bp

>T237140 NZ_LR778152:3680581-3680688 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 143 bp

>AT237140 NZ_CP092784:2558390-2558532 [Enterococcus sp. LX10]
TGTGCTATAATGAAAACGAAAAGAGAGATATGCTTCAACATACCTCTCTGATGCAGAGCCGTTTAAGACGGTGACCGATT
TTGTTACAAAAAATAACCGTACCGATCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAACA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References