Detailed information of TA system TA236773

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2238110..2238327
• Replicon: chromosome
• Accession: NZ_CP092631
• Organism: Bacillus subtilis strain YB-15

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: MKS87_RS11495
• Protein ID: WP_019712271.1
• Coordinates: 2238110..2238286 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2238227..2238327 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MKS87_RS11425 (2233144)	2233144..2233290	-	147	WP_240304193.1	hypothetical protein	-
MKS87_RS11430 (2233309)	2233309..2233548	-	240	WP_240304194.1	hypothetical protein	-
MKS87_RS11435 (2233545)	2233545..2233739	-	195	WP_240304195.1	hypothetical protein	-
MKS87_RS11440 (2233736)	2233736..2233951	-	216	WP_041906973.1	hypothetical protein	-
MKS87_RS11445 (2234005)	2234005..2234184	-	180	WP_240304196.1	hypothetical protein	-
MKS87_RS11450 (2234217)	2234217..2234486	-	270	WP_240304197.1	hypothetical protein	-
MKS87_RS11455 (2234518)	2234518..2234721	-	204	WP_240304198.1	hypothetical protein	-
MKS87_RS11460 (2234727)	2234727..2234960	-	234	WP_240304199.1	hypothetical protein	-
MKS87_RS11465 (2235011)	2235011..2235265	-	255	WP_032677190.1	hypothetical protein	-
MKS87_RS11470 (2235308)	2235308..2235529	-	222	WP_240304200.1	hypothetical protein	-
MKS87_RS11475 (2235526)	2235526..2235978	-	453	WP_240304201.1	hypothetical protein	-
MKS87_RS11480 (2236308)	2236308..2237525	-	1218	WP_240304202.1	hypothetical protein	-
MKS87_RS11485 (2237607)	2237607..2237795	-	189	WP_240304203.1	hypothetical protein	-
MKS87_RS11490 (2237840)	2237840..2238091	-	252	WP_080010576.1	hypothetical protein	-
MKS87_RS11495 (2238110)	2238110..2238286	-	177	WP_019712271.1	hypothetical protein	Toxin
- (2238227)	2238227..2238327	+	101	NuclAT_0	-	Antitoxin
- (2238227)	2238227..2238327	+	101	NuclAT_0	-	Antitoxin
- (2238227)	2238227..2238327	+	101	NuclAT_0	-	Antitoxin
- (2238227)	2238227..2238327	+	101	NuclAT_0	-	Antitoxin
MKS87_RS11500 (2238825)	2238825..2239436	-	612	WP_074794693.1	hypothetical protein	-
MKS87_RS11505 (2239629)	2239629..2239958	-	330	WP_032721651.1	helix-turn-helix transcriptional regulator	-
MKS87_RS11510 (2240906)	2240906..2241100	+	195	WP_072692657.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2168875..2296050	127175

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (8-95)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6864.42 Da
• Isoelectric Point: 12.8833

>T236773 WP_019712271.1 NZ_CP092631:c2238286-2238110 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T236773 NZ_LR738721:c1863138-1862809 [Streptococcus suis]
ATGGAATTTGAGTCTTATTCAGTGATACTTGCTCCAGCAGTGGAGAAGGAATTGGCAGTTATTTACGCCTATTTTTCGGA
ACAGTTCTCAGAAGAAATTGCCAAAAGACGAATTGGGATGATTGTCGAAGCATTAGAGAGTTTGCAAATTTTTCCTGAAC
GTGGTTTTAACGCCGATAACCGTTTTGGTAAGCAGATAGACCCGCCTCATCTAACCCGAGGCTATGTCGTTGGAAAAGAC
TACATCGCCCTCTATCGCGTAGTGAAAAATGAAGTTCGAGTTGGTCATCTTTTTGCGACCAAGAGTGATTATGTGAAGTT
GTTGAAGTGA

Antitoxin

Nucleotide

• Length: 101 bp

>AT236773 NZ_CP092631:2238227-2238327 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGAAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin