Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-RNAII/- |
Location | 2766222..2766482 | Replicon | chromosome |
Accession | NZ_CP092576 | ||
Organism | Enterococcus faecalis strain VRE-WC031 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | MKI49_RS13790 | Protein ID | WP_021164442.1 |
Coordinates | 2766381..2766482 (-) | Length | 34 a.a. |
Antitoxin (RNA)
Gene name | RNAII | ||
Locus tag | - | ||
Coordinates | 2766222..2766427 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MKI49_RS13765 (2761876) | 2761876..2762829 | - | 954 | WP_002368426.1 | siderophore ABC transporter substrate-binding protein | - |
MKI49_RS13770 (2762868) | 2762868..2763623 | - | 756 | WP_002354962.1 | ATP-binding cassette domain-containing protein | - |
MKI49_RS13775 (2763620) | 2763620..2764585 | - | 966 | WP_002368427.1 | iron chelate uptake ABC transporter family permease subunit | - |
MKI49_RS13780 (2764582) | 2764582..2765529 | - | 948 | WP_002368428.1 | iron chelate uptake ABC transporter family permease subunit | - |
MKI49_RS13785 (2765714) | 2765714..2766166 | + | 453 | WP_002368429.1 | YueI family protein | - |
- (2766222) | 2766222..2766427 | + | 206 | NuclAT_11 | - | Antitoxin |
- (2766256) | 2766256..2766444 | + | 189 | NuclAT_4 | - | - |
MKI49_RS13790 (2766381) | 2766381..2766482 | - | 102 | WP_021164442.1 | putative holin-like toxin | Toxin |
MKI49_RS13795 (2766673) | 2766673..2768943 | - | 2271 | WP_002368430.1 | bifunctional glutamate--cysteine ligase/glutathione synthetase | - |
MKI49_RS13800 (2769114) | 2769114..2769614 | + | 501 | WP_024041671.1 | cysteine hydrolase family protein | - |
MKI49_RS13805 (2770013) | 2770013..2770909 | + | 897 | WP_002368434.1 | YitT family protein | - |
MKI49_RS13810 (2770960) | 2770960..2771358 | - | 399 | WP_002354951.1 | glyoxalase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 34 a.a. Molecular weight: 3625.38 Da Isoelectric Point: 4.5869
>T236672 WP_021164442.1 NZ_CP092576:c2766482-2766381 [Enterococcus faecalis]
MSIEATLELMISFATLVALLIFGILEATKNDKK
MSIEATLELMISFATLVALLIFGILEATKNDKK
Download Length: 102 bp
>T236672 NZ_LR699553:3466191-3466472 [Paraburkholderia sp. Msb3]
ATGATCACGACATTCGGCGACAAAACTACGGCGAGAATTTTTCAAGGCAGGTTCGTGTACTCACTGCCGCTTCACATGCA
AACGCTCGCGCACCGCAAGCTGCTGCTGATCGACGCCGCAGAGTCCGTTTGCGATCTGCACGCGCCGCCGGGCAACCGGC
TGGAAGCGTTGCAAAGCCAGCGCAGCGGGCAATGGAGTATCAGGATCAATGCGCAATGGCGCCTCGGTTTTCATTTCGTC
GACGGGGAGGCACTGAATGTCGAGATTGTCGACTATCACTGA
ATGATCACGACATTCGGCGACAAAACTACGGCGAGAATTTTTCAAGGCAGGTTCGTGTACTCACTGCCGCTTCACATGCA
AACGCTCGCGCACCGCAAGCTGCTGCTGATCGACGCCGCAGAGTCCGTTTGCGATCTGCACGCGCCGCCGGGCAACCGGC
TGGAAGCGTTGCAAAGCCAGCGCAGCGGGCAATGGAGTATCAGGATCAATGCGCAATGGCGCCTCGGTTTTCATTTCGTC
GACGGGGAGGCACTGAATGTCGAGATTGTCGACTATCACTGA
Antitoxin
Download Length: 206 bp
>AT236672 NZ_CP092576:2766222-2766427 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTTATACCAACG
CCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGT
TATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTA
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTTATACCAACG
CCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGT
TATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|