Detailed information of TA system TA236254

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 938178..938358
• Replicon: chromosome
• Accession: NZ_CP092475
• Organism: Staphylococcus aureus strain P5

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: MKD48_RS05010
• Protein ID: WP_001801861.1
• Coordinates: 938263..938358 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	938178..938235 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MKD48_RS04975	933689..934924	+	1236	WP_001215400.1	IS21 family transposase	-
MKD48_RS04980	934936..935703	+	768	WP_001095317.1	IS21-like element helper ATPase IstB	-
MKD48_RS04985	935764..936627	-	864	Protein_944	lipase	-
MKD48_RS04990	936672..937112	+	441	WP_000759947.1	DUF1433 domain-containing protein	-
MKD48_RS04995	937318..937695	+	378	WP_001036002.1	DUF1433 domain-containing protein	-
MKD48_RS05000	937889..938061	+	173	Protein_947	transposase	-
MKD48_RS05005	938039..938140	-	102	WP_001791232.1	hypothetical protein	-
-	938178..938235	+	58	-	-	Antitoxin
MKD48_RS05010	938263..938358	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
MKD48_RS05015	938781..939005	+	225	WP_001805677.1	IS3 family transposase	-
MKD48_RS05020	939187..939569	+	383	Protein_951	hypothetical protein	-
MKD48_RS05025	939580..939756	+	177	WP_000375476.1	hypothetical protein	-
MKD48_RS05030	939758..939943	+	186	WP_000809864.1	hypothetical protein	-
MKD48_RS05035	940058..940698	+	641	Protein_954	ImmA/IrrE family metallo-endopeptidase	-
MKD48_RS05040	940895..941467	-	573	WP_000414208.1	hypothetical protein	-
MKD48_RS05045	941568..941909	-	342	WP_000627536.1	DUF3969 family protein	-
MKD48_RS05050	941950..942576	-	627	WP_000669029.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	selk	919746..945134	25388

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T236254 WP_001801861.1 NZ_CP092475:c938358-938263 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T236254 NZ_LR215973:c1142213-1141923 [Nocardia cyriacigeorgica]
GTGAGCCGGTATCTTCTCTCCCCCGCCGCGCAGGCCGATATCGATAACATCTTCGAATTCACCTGCGAGCAATGGGGATT
CGAGCAGGCCGAGAAGTATGTACGCGAACTCCAGTACGCCATCGAGCGCGCCGTGGCGAACCCCGGCATCGGCCGGGCGT
GTGATGAGATCCGCCCCGGCTACCGTGCACTTCCCGCTGGATCACACACCCTCTACTACCGGATCAACGGGGACGTGATC
GATGTCGTGCGAATCCTGCACCAGCGCATGGACATCGACCGCAACCTGTGA

Antitoxin

Nucleotide

• Length: 58 bp

>AT236254 NZ_CP092475:938178-938235 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin