Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1481012..1481548 Replicon chromosome
Accession NZ_CP092471
Organism Qipengyuania spongiae strain PHS-Z21

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag L1F33_RS07365 Protein ID WP_265557289.1
Coordinates 1481012..1481281 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag L1F33_RS07370 Protein ID WP_265557290.1
Coordinates 1481285..1481548 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L1F33_RS07350 (L1F33_07320) 1477843..1478502 + 660 WP_265557286.1 fructose-6-phosphate aldolase -
L1F33_RS07355 (L1F33_07325) 1478515..1480335 + 1821 WP_265557287.1 cobaltochelatase subunit CobT -
L1F33_RS07360 (L1F33_07330) 1480337..1481011 + 675 WP_265557288.1 nitroreductase -
L1F33_RS07365 (L1F33_07335) 1481012..1481281 - 270 WP_265557289.1 Txe/YoeB family addiction module toxin Toxin
L1F33_RS07370 (L1F33_07340) 1481285..1481548 - 264 WP_265557290.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
L1F33_RS07375 (L1F33_07345) 1481626..1483077 + 1452 WP_265557291.1 cysteine--tRNA ligase -
L1F33_RS07380 (L1F33_07350) 1483074..1484033 + 960 WP_265557292.1 D-2-hydroxyacid dehydrogenase -
L1F33_RS07385 (L1F33_07355) 1484042..1484398 - 357 WP_265557293.1 hypothetical protein -
L1F33_RS07390 (L1F33_07360) 1484388..1484600 - 213 WP_265557294.1 hypothetical protein -
L1F33_RS07395 (L1F33_07365) 1484739..1485425 + 687 WP_265557295.1 XRE family transcriptional regulator -
L1F33_RS07400 (L1F33_07370) 1485532..1486173 + 642 WP_265557296.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10970.53 Da        Isoelectric Point: 9.4004

>T236239 WP_265557289.1 NZ_CP092471:c1481281-1481012 [Qipengyuania spongiae]
MQLLFDRDAWADYLFWQDRDRKLLKRINRMIKECQRTPYEGIGKPEPLKEDLSGYWSRRITDEHRLVYRVVGKGDTETFQ
IAQCRYHYR

Download         Length: 270 bp

>T236239 NZ_LR213458:c3869735-3869424 [Shigella sonnei]
ATGCACATCATTTCTAAAGCGCCATTTGAAGAGTCTGCGCGTAAATATCCTAACGACGCTCTGGCTCTTCAGGCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACGCCAGAAGAGATGCGAACGGCGTTTCCCAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTAGGTGGGAACAACCTAAGGGTGATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACTAATCACGCCGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9837.02 Da        Isoelectric Point: 4.3108

>AT236239 WP_265557290.1 NZ_CP092471:c1481548-1481285 [Qipengyuania spongiae]
MDVTTYTDARKNLKAVMDRVVDDCDHTVITRQNGEPVVMLSLSEWNSLRETAYLLSSPKNAERLRDSIARLDAGEGEVRE
LIEVVDD

Download         Length: 264 bp

>AT236239 NZ_LR213458:c3869427-3869008 [Shigella sonnei]
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGTAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAATATGAAAACAACAACCAAGAGTTTGCAGAGTTCGACAAAGCCGTTGCGGCAATGCCTGTT
GGCGTGGCGTTACTTCGCACGCTGATTGATCAACATAATCTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
CCTGGTCAGTCAGATTTTGTCTGGACAACGATCCCTGACGATATCCCACATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References