Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2380883..2381067 Replicon chromosome
Accession NZ_CP092447
Organism Staphylococcus aureus strain SYN

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LXM97_RS11605 Protein ID WP_000482647.1
Coordinates 2380960..2381067 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2380883..2380943 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LXM97_RS11590 (LXM97_11590) 2376393..2376560 - 168 WP_031845053.1 hypothetical protein -
LXM97_RS11595 (LXM97_11595) 2376791..2378524 - 1734 WP_000488493.1 ABC transporter ATP-binding protein -
LXM97_RS11600 (LXM97_11600) 2378600..2380312 - 1713 WP_001064821.1 ABC transporter ATP-binding protein -
- 2380883..2380943 + 61 - - Antitoxin
LXM97_RS11605 (LXM97_11605) 2380960..2381067 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
LXM97_RS11610 (LXM97_11610) 2381200..2381586 - 387 WP_000779353.1 flippase GtxA -
LXM97_RS11615 (LXM97_11615) 2381854..2382996 + 1143 WP_001176863.1 glycerate kinase -
LXM97_RS11620 (LXM97_11620) 2383056..2383716 + 661 Protein_2240 hypothetical protein -
LXM97_RS11625 (LXM97_11625) 2383899..2385110 + 1212 WP_001191921.1 multidrug effflux MFS transporter -
LXM97_RS11630 (LXM97_11630) 2385233..2385706 - 474 WP_000456483.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T236123 WP_000482647.1 NZ_CP092447:c2381067-2380960 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T236123 NZ_LR135357:c2318533-2318267 [Enterococcus faecium]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAAACGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTAGAAATT
TATTCTGCCTGGACACATTATGAGTGA

Antitoxin


Download         Length: 61 bp

>AT236123 NZ_CP092447:2380883-2380943 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References