Detailed information of TA system TA236069

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 6819267..6819790
• Replicon: chromosome
• Accession: NZ_CP092417
• Organism: Endozoicomonas sp. SCSIO W0465

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: MJO57_RS30845
• Protein ID: WP_252027148.1
• Coordinates: 6819536..6819790 (+)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: MJO57_RS30840
• Protein ID: WP_252027147.1
• Coordinates: 6819267..6819521 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10230.64 Da
• Isoelectric Point: 8.4867

>T236069 WP_252027148.1 NZ_CP092417:6819536-6819790 [Endozoicomonas sp. SCSIO W0465]
ITLSWAEEAWEDFQYWLDNDKPKARKLRKLIKECMRTPFEGTGKPEPLKGNFSGFWSRRIDQEHRLVYAYSNDNLFILQC
RFHY

Nucleotide

• Length: 255 bp

>T236069 NZ_LR135257:52331-52588 [Enterococcus faecium]
ATGATTAAGGCTTGGTCTGATGATGCTTGGGATGATTATCTTTATTGGCATGAGCAAGGAAACAAAAGCAATATAAAAAA
GATTAACAAGTTAATAAAAGATATCGATCGTTCCCCCTTTGCTGGATTAGGAAAACCTGAGCCATTAAAGCATGATTTAT
CTGGAAAATGGTCCAGAAGAATTACAGATGAACATAGACTGATATATAGAGTTGAAAATGAAACGATATTTATTTATTCT
GCAAAAGATCACTATTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9539.88 Da
• Isoelectric Point: 7.2017

>AT236069 WP_252027147.1 NZ_CP092417:6819267-6819521 [Endozoicomonas sp. SCSIO W0465]
MNVVSYTEMRKNLKAVLDSVVNDATHTVIHRRDAEDAVVMSKESYDSLMETLYLLSSPENARRLKSAAEQFKANKGIKRD
LPEL

Nucleotide

• Length: 255 bp

>AT236069 NZ_LR135257:52069-52338 [Enterococcus faecium]
ATGGAAGCAGTAGCTTATTCAAATTTCCGCCAAAATTTACGTAGTTATATGAAACAAGTTAATGAGGATGCTGAAACACT
TATTGTAACAAGTAAAGATGTAGAAGATACAGTTGTTGTATTATCAAAAAGAGATTATGATTCTATGCAAGAAACGTTGA
GAACACTTTCTAATAATTACGTCATGGAAAAAATTCGTCGAGGAGATGAACAATTCTCCAAAGGTGCATTTAAAACACAT
GACTTAATCGAGGTTGAATCTGATGATTAA