Detailed information of TA system TA235994

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): DinJ-YafQ (relBE)/YafQ-RelB
• Location: 1462578..1463145
• Replicon: chromosome
• Accession: NZ_CP092373
• Organism: Pantoea sp. Z09

Toxin (Protein)

• Gene name: yafQ
• Uniprot ID: -
• Locus tag: MC269_RS06935
• Protein ID: WP_239954603.1
• Coordinates: 1462867..1463145 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: -
• Locus tag: MC269_RS06930
• Protein ID: WP_239954602.1
• Coordinates: 1462578..1462838 (+)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MC269_RS06910	1458345..1459271	+	927	WP_239954598.1	glyoxylate/hydroxypyruvate reductase A	-
MC269_RS06915	1459271..1460395	+	1125	WP_239954599.1	M20 aminoacylase family protein	-
MC269_RS06920	1460524..1461840	+	1317	WP_239954601.1	4-aminobutyrate--2-oxoglutarate transaminase	-
MC269_RS06925	1461982..1462494	+	513	WP_081140041.1	Lrp/AsnC family transcriptional regulator	-
MC269_RS06930	1462578..1462838	+	261	WP_239954602.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
MC269_RS06935	1462867..1463145	+	279	WP_239954603.1	type II toxin-antitoxin system YafQ family toxin	Toxin
MC269_RS06940	1463335..1463781	+	447	WP_239954604.1	GNAT family N-acetyltransferase	-
MC269_RS06945	1463798..1465849	+	2052	WP_239954605.1	hydantoinase/oxoprolinase family protein	-
MC269_RS06950	1465852..1467813	+	1962	WP_239954606.1	hydantoinase B/oxoprolinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-92)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-83)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 11117.98 Da
• Isoelectric Point: 10.2533

>T235994 WP_239954603.1 NZ_CP092373:1462867-1463145 [Pantoea sp. Z09]
MAKQREIAYSNQFYKDVKKMQKRRKKMDKLKTLMSLLMNDRLPLPAAYKDHPLQGNYRGYRDAHIEPDWLLIYKLTDELI
RFERTGTHADLF

Nucleotide

• Length: 279 bp

>T235994 NZ_LR134533:c2145009-2144869 [Neisseria weaveri]
ATGAAAAAATTCGCACTGATCGCTCTTACCGCCGTTTCTTTCTTGGCCGGTTGCAATACCATTGCCGGCGCAGGTAAAGA
TGTCAGCGCTGCAGGTAACGCTGTAACCAACACGGCACAAGACGTTAAATCTGCTATGTAA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9356.80 Da
• Isoelectric Point: 5.1351

>AT235994 WP_239954602.1 NZ_CP092373:1462578-1462838 [Pantoea sp. Z09]
MPTNAFVRARIDETLKNEAAAVLAEMGLTVSDLVRITLTKVAKEKALPFDLRIPNDITASSIEASEQGKGVKKAKDEKDL
FDQLGI

Nucleotide

• Length: 261 bp

>AT235994 NZ_LR134533:c2145162-2145040 [Neisseria weaveri]
ATGAAAAAATTAGCTTTAATCACAATTGCTACCGTAGCATTGCTAACCGGCTGCAACACCATTGCCGGTGCAGGTAAAGA
TGTCAGCGCAGTAGGACGCGCTGTTACCCATGTTGCCCAATAA