Detailed information of TA system TA235971

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-SR6/-
• Location: 2184697..2185026
• Replicon: chromosome
• Accession: NZ_CP092369
• Organism: Bacillus subtilis strain ZW

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: MID01_RS11140
• Protein ID: WP_109962751.1
• Coordinates: 2184697..2184948 (-)
• Length: 84 a.a.

Antitoxin (RNA)

Gene name	SR6
Locus tag	-
Coordinates	2184926..2185026 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MID01_RS11100	2180078..2180413	-	336	WP_109962744.1	hypothetical protein	-
MID01_RS11105	2180451..2180747	-	297	WP_109962745.1	hypothetical protein	-
MID01_RS11110	2180823..2181068	-	246	WP_109962746.1	hypothetical protein	-
MID01_RS11115	2181068..2181268	-	201	WP_109962747.1	hypothetical protein	-
MID01_RS11120	2181306..2182205	-	900	WP_109962748.1	hypothetical protein	-
MID01_RS11125	2182317..2182748	-	432	WP_109962749.1	hypothetical protein	-
MID01_RS11130	2183165..2184382	-	1218	WP_109962750.1	hypothetical protein	-
MID01_RS11135	2184464..2184652	-	189	WP_003230987.1	hypothetical protein	-
MID01_RS11140	2184697..2184948	-	252	WP_109962751.1	hypothetical protein	Toxin
-	2184926..2185026	+	101	-	-	Antitoxin
MID01_RS11145	2184967..2185143	-	177	WP_109962752.1	hypothetical protein	-
-	2185084..2185184	+	101	NuclAT_1	-	-
-	2185084..2185184	+	101	NuclAT_1	-	-
-	2185084..2185184	+	101	NuclAT_1	-	-
-	2185084..2185184	+	101	NuclAT_1	-	-
MID01_RS11150	2186175..2186369	+	195	WP_004399291.1	hypothetical protein	-
MID01_RS11155	2186409..2188916	+	2508	WP_109962753.1	DNA-directed RNA polymerase YonO	-
MID01_RS11160	2189180..2189455	+	276	WP_072692660.1	HU family DNA-binding protein	-
MID01_RS11165	2189878..2189989	+	112	Protein_2154	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2116127..2265019	148892

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (8-106)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 10072.08 Da
• Isoelectric Point: 10.0301

>T235971 WP_109962751.1 NZ_CP092369:c2184948-2184697 [Bacillus subtilis]
MNFSFSSYPYYNMIKHIANMKRFSLWFTHITFIGLFLMFQLIKDYFSNEAQTLINTIFVVTCIIAILLWIIYFVFLKLRN
KSH

Nucleotide

• Length: 252 bp

>T235971 NZ_LR134520:1874554-1874889 [Streptococcus agalactiae]
TTGGACTATAAGAAATATCAGATTATCTATGCTCCTGATGTTTTAGAGAAGCTAAAAGAAATTCGTGATTATATTTCCCA
AAACTATTCCTCAACATCAGGTCAGCGTAAAATGGAGCAAATCATTAATGACATAGAAAAACTTGAAGTTTTCCCAGAAG
TTGGTTTTGATGCCGATGAAAAATATGGTTCAGAAATCAGCAATTATCACAGTACTAGAGGTTACACCTTAAGTAAAGAT
TATATTGTCCTATACCATATCGAAGAGGAAGAGAATAGGGTTGTCATTGATTACTTGCTTCCTACTCGAAGCGACTATAT
GAAATTGTTTAAATAG

Antitoxin

Nucleotide

• Length: 101 bp

>AT235971 NZ_CP092369:2184926-2185026 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATATGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT

Structures

Antitoxin