Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 283547..284160 Replicon chromosome
Accession NZ_CP092344
Organism Rhizobium gallicum strain M101

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag L2W42_RS01340 Protein ID WP_239597681.1
Coordinates 283547..283843 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag L2W42_RS01345 Protein ID WP_239597682.1
Coordinates 283852..284160 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2W42_RS01315 (L2W42_01315) 279243..279821 - 579 WP_239597677.1 TRAP transporter small permease -
L2W42_RS01320 (L2W42_01320) 279964..280941 - 978 WP_239597678.1 TRAP transporter substrate-binding protein -
L2W42_RS01325 (L2W42_01325) 281468..282487 + 1020 WP_239597679.1 Gfo/Idh/MocA family oxidoreductase -
L2W42_RS01330 (L2W42_01330) 282602..282793 + 192 WP_022716877.1 DUF3008 family protein -
L2W42_RS01335 (L2W42_01335) 283023..283358 + 336 WP_239597680.1 hypothetical protein -
L2W42_RS01340 (L2W42_01340) 283547..283843 + 297 WP_239597681.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L2W42_RS01345 (L2W42_01345) 283852..284160 + 309 WP_239597682.1 HigA family addiction module antitoxin Antitoxin
L2W42_RS01350 (L2W42_01350) 284464..284613 - 150 Protein_266 ISAzo13 family transposase -
L2W42_RS01355 (L2W42_01355) 284939..286234 + 1296 WP_239597683.1 hypothetical protein -
L2W42_RS01360 (L2W42_01360) 286269..287708 - 1440 WP_239597684.1 MFS transporter -
L2W42_RS01365 (L2W42_01365) 287806..288237 + 432 WP_239597685.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-95)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(3-95)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11732.12 Da        Isoelectric Point: 6.4856

>T235935 WP_239597681.1 NZ_CP092344:283547-283843 [Rhizobium gallicum]
MIVGFRDEWLRAYFVEDVHSRNIPADLESRLFRKLQMIDDATTDQDLRVPPSNHFEKLRGNLEGLHSIRVNRQWRVVFRW
DGSRGEASEVYLDDHSYR

Download         Length: 297 bp

>T235935 NZ_LR134494:2072629-2072709 [Serratia quinivorans]
AATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATCGTATTCGGTCTTTTTT
T

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11541.42 Da        Isoelectric Point: 10.1840

>AT235935 WP_239597682.1 NZ_CP092344:283852-284160 [Rhizobium gallicum]
MLMTKRKPATVGEILREEFMQPLDLTQAVLAEAMGVQRKHVNELCNDRRNVTAATALILARVFGNSPDFWLNVQRRSDLW
DAMHSPKELARIERAKPLATAA

Download         Length: 309 bp

>AT235935 NZ_LR134494:c2072717-2072591 [Serratia quinivorans]
AACAGGTTAAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAA
GTTGGCATTTTGTGCAAAGCTTGTTCAGCCGTGCACTTTAAGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References