Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafN-yafO (relBE)/YafO-YafN
Location 2075661..2076364 Replicon chromosome
Accession NZ_CP092106
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name yafO Uniprot ID -
Locus tag L3Q72_RS09205 Protein ID WP_275129654.1
Coordinates 2075951..2076364 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name yafN Uniprot ID -
Locus tag L3Q72_RS09200 Protein ID WP_275129653.1
Coordinates 2075661..2075954 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q72_RS09175 (L3Q72_09165) 2071558..2072478 - 921 WP_275129648.1 hypothetical protein -
L3Q72_RS09180 (L3Q72_09170) 2072578..2073477 + 900 WP_275129649.1 LysR family transcriptional regulator -
L3Q72_RS09185 (L3Q72_09175) 2073557..2074450 - 894 WP_275129650.1 haloalkane dehalogenase -
L3Q72_RS09190 (L3Q72_09180) 2074582..2075145 + 564 WP_275129651.1 TetR/AcrR family transcriptional regulator -
L3Q72_RS09195 (L3Q72_09185) 2075138..2075497 + 360 WP_275129652.1 MmcQ/YjbR family DNA-binding protein -
L3Q72_RS09200 (L3Q72_09190) 2075661..2075954 + 294 WP_275129653.1 hypothetical protein Antitoxin
L3Q72_RS09205 (L3Q72_09195) 2075951..2076364 + 414 WP_275129654.1 type II toxin-antitoxin system YafO family toxin Toxin
L3Q72_RS09210 (L3Q72_09200) 2076424..2077713 - 1290 WP_275129655.1 NAD(P)/FAD-dependent oxidoreductase -
L3Q72_RS09215 (L3Q72_09205) 2078053..2078595 - 543 WP_275129656.1 alpha/beta hydrolase YcfP -
L3Q72_RS09220 (L3Q72_09210) 2078684..2079538 - 855 WP_275129657.1 phosphotransferase -
L3Q72_RS09225 (L3Q72_09215) 2079618..2080208 - 591 WP_275129658.1 penicillin-binding protein activator LpoB -
L3Q72_RS09230 (L3Q72_09220) 2080225..2080611 - 387 WP_275132093.1 YcfL family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin YafO

(34-135)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15917.27 Da        Isoelectric Point: 7.1165

>T235709 WP_275129654.1 NZ_CP092106:2075951-2076364 [Vibrio sp. JC009]
VSDKLLKVRVFKHKILIDALTKDELEGLTKDFRVYKETGQKPDIFGRDEAYDHPDTLPILKSEEVKHIHLSANDAPFLSK
IQFYQTSDKHLVYCQGWEDPNCFLLIAILAPNAHEQARNRTIMHNLGLIAEKFRQQF

Download         Length: 414 bp

>T235709 NZ_LR134333:1188547-1188957 [Klebsiella oxytoca]
GTGGTCCTGTGGCAATCTGATTTACGCATCTCGTGGCGAGCGCAATGGTTCTCACTGTTGATGCACGGCGTGGTGGCGGC
GCTGGTGCTGGTGTTGCCCTGGCCGCTGAGCTATACCCCGCTGTGGCTGATACTGCTGTCGCTGGTGGTGTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCAGACAGGGGGAAATAAAGTTGCTGATTGACTCTCGCCTGCGCTGGCAAAAAGCG
GAGTGGGATATCGTCGGCACCCCGTGGGTAATCAATAGCGGAATGCTGCTGCGTCTGCGAAATACGGAAAACCAACGCAC
TCAGCATCTATGGGTGGCGGCGGATAGCATGGACGCGGGCGAGTGGCGCGATCTGCGTCGGCTGGTGTTACAGAAACCGA
CGCAAGATTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10561.90 Da        Isoelectric Point: 4.4915

>AT235709 WP_275129653.1 NZ_CP092106:2075661-2075954 [Vibrio sp. JC009]
MKTSTIYAEKAVSSSEARKHFKDCLSGEPVVVLSNNEPAGYMMSATFFEGLMKALEGKGTDSISSFRPMSARLDVIAHLN
AQALAELDENDLGEFQE

Download         Length: 294 bp

>AT235709 NZ_LR134333:1188300-1188566 [Klebsiella oxytoca]
ATGGATATTAACAATAAAGCTCGCATCCACTGGGCATGCCGCCGGGGAATGCGTGAACTCGATATCTCCATCATGCCGTT
TTTTGAGCATGAGTACGATACGCTCAGTGATGACGATAAGCGGTTGTTCATCCGCCTGCTGGAAAATGACGATCCGGACC
TGTTCAACTGGTTGATGAACCATGGCGAACCGGCTGATGCAGAACTGCAGCGGATGGTAAAATTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References