Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1654633..1655404 Replicon chromosome
Accession NZ_CP092106
Organism Vibrio sp. JC009

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag L3Q72_RS07600 Protein ID WP_275132041.1
Coordinates 1654633..1655100 (-) Length 156 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag L3Q72_RS07605 Protein ID WP_275132042.1
Coordinates 1655090..1655404 (-) Length 105 a.a.

Genomic Context


L3Q72_RS07570L3Q72_RS07585L3Q72_RS07610L3Q72_RS07620L3Q72_RS07640L3Q72_RS07560L3Q72_RS07565L3Q72_RS07575L3Q72_RS07580L3Q72_RS07590L3Q72_RS07595L3Q72_RS07600L3Q72_RS07605L3Q72_RS07615L3Q72_RS07625L3Q72_RS07630L3Q72_RS07635
Location: 1652211..1652561 (351 bp)
Type: Others
Protein ID: WP_275130849.1
Location: 1653576..1653833 (258 bp)
Type: Others
Protein ID: Protein_1461
Location: 1655488..1655838 (351 bp)
Type: Others
Protein ID: Protein_1466
Location: 1656935..1657759 (825 bp)
Type: Others
Protein ID: WP_275132044.1
Location: 1659383..1660390 (1008 bp)
Type: Others
Protein ID: WP_275132048.1
Location: 1649763..1650521 (759 bp)
Type: Others
Protein ID: WP_275130851.1
Location: 1650511..1652007 (1497 bp)
Type: Others
Protein ID: WP_275130850.1
Location: 1652718..1652939 (222 bp)
Type: Others
Protein ID: WP_275132037.1
Location: 1652939..1653439 (501 bp)
Type: Others
Protein ID: WP_275132038.1
Location: 1653871..1654161 (291 bp)
Type: Others
Protein ID: WP_275132039.1
Location: 1654204..1654479 (276 bp)
Type: Others
Protein ID: WP_275132040.1
Location: 1654633..1655100 (468 bp)
Type: Toxin
Protein ID: WP_275132041.1
Location: 1655090..1655404 (315 bp)
Type: Antitoxin
Protein ID: WP_275132042.1
Location: 1655899..1656783 (885 bp)
Type: Others
Protein ID: WP_275132043.1
Location: 1657937..1658305 (369 bp)
Type: Others
Protein ID: WP_275132045.1
Location: 1658319..1658528 (210 bp)
Type: Others
Protein ID: WP_275132046.1
Location: 1658582..1659061 (480 bp)
Type: Others
Protein ID: WP_275132047.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
L3Q72_RS07560 (L3Q72_07550)1649763..1650521-759WP_275130851.1IS21-like element helper ATPase IstB-
L3Q72_RS07565 (L3Q72_07555)1650511..1652007-1497WP_275130850.1IS21 family transposase-
L3Q72_RS07570 (L3Q72_07560)1652211..1652561+351WP_275130849.1hypothetical protein-
L3Q72_RS07575 (L3Q72_07565)1652718..1652939-222WP_275132037.1hypothetical protein-
L3Q72_RS07580 (L3Q72_07570)1652939..1653439-501WP_275132038.1hypothetical protein-
L3Q72_RS07585 (L3Q72_07575)1653576..1653833+258Protein_1461carboxypeptidase M32-
L3Q72_RS07590 (L3Q72_07580)1653871..1654161-291WP_275132039.1type II toxin-antitoxin system RelE/ParE family toxin-
L3Q72_RS07595 (L3Q72_07585)1654204..1654479-276WP_275132040.1hypothetical protein-
L3Q72_RS07600 (L3Q72_07590)1654633..1655100-468WP_275132041.1type II toxin-antitoxin system YhaV family toxinToxin
L3Q72_RS07605 (L3Q72_07595)1655090..1655404-315WP_275132042.1type II toxin-antitoxin system PrlF family antitoxinAntitoxin
L3Q72_RS07610 (L3Q72_07600)1655488..1655838+351Protein_1466hypothetical protein-
L3Q72_RS07615 (L3Q72_07605)1655899..1656783-885WP_275132043.1LysR family transcriptional regulator-
L3Q72_RS07620 (L3Q72_07610)1656935..1657759+825WP_275132044.1NAD(P)-dependent oxidoreductase-
L3Q72_RS07625 (L3Q72_07615)1657937..1658305-369WP_275132045.1ATP-binding protein-
L3Q72_RS07630 (L3Q72_07620)1658319..1658528-210WP_275132046.1PAS domain-containing protein-
L3Q72_RS07635 (L3Q72_07625)1658582..1659061-480WP_275132047.1GNAT family protein-
L3Q72_RS07640 (L3Q72_07630)1659383..1660390+1008WP_275132048.1AraC family transcriptional regulator-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1652718..166954016822


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(9-143)

Antitoxin

(7-102)


Sequences


Toxin        


Download         Length: 156 a.a.        Molecular weight: 18219.87 Da        Isoelectric Point: 10.0067

>T235707 WP_275132041.1 NZ_CP092106:c1655100-1654633 [Vibrio sp. JC009]
MKINSWNCFTHSCFSEQYNELVEKVKLLKEKHPTTFQKKSATKLLFAIQKLIFEVIPTNPALPSYRHGGTAGINRHWFRA
KFFKGRFRLFFRYDHKSKTIIYGWVNDESTLRTYGSKSDAYSVFKKMLVDGTPPDAWDDLKRQSVDVSELIEDRD

Download         Length: 468 bp

>T235707 NZ_LR134331:c2597339-2596956 [Lacticaseibacillus rhamnosus]
ATGGATGTAACAGTCAAACGCGGGGATGTATTTTTCGCCGATTTATCGCCGGTTGTCGGGTCGGAACAAGGCGGCAACCG
GCCCGTACTTATTATTCAAAACAATGTTGGTAACCATTATAGCCCCACTGTTATCGTGGCTGCCATTACCTCCAAAATCC
AAAAACCCAAAATGCCCACCCATGTCGGTTTGCGCGCCAAGCAAGACGGGGTTGAGCGTAATTCAGTCATTTTGCTTGAA
CAGATTCGTACAATTGATAAGCAACGGTTACAGGCACGCGTTACCGCTCTTTCAAGTGCCAAAATGGCAGCGGTGGATCG
GGCACTGGCGATATCGGTCGGACTCGTCAGCTTGCCTAAGCCGAAAACATATAATAAAAACTAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11362.71 Da        Isoelectric Point: 4.0640

>AT235707 WP_275132042.1 NZ_CP092106:c1655404-1655090 [Vibrio sp. JC009]
MELLAVESSVTSRYQTTIPQEIRTALGLEKNDKIHYGLNERGEVVLSRVAQHVDPTVGAFLSLIDQDIKNGKSVSSLSAL
NPMGLELTAGMDVDLDSELFDDED

Download         Length: 315 bp

>AT235707 NZ_LR134331:c2597607-2597359 [Lacticaseibacillus rhamnosus]
ATGAAGAAGGAAACGTCAGTAACGGTCGCGCTTGATAGTGCTATCAAAGCGCGTTTGGATGCCTATTGCGAGTTGAATGA
TATGGGTGTTCAGGATGTCATTACTGAAGCAGTGGCGAAGTTTTTGCAGTCACAAGCACCTGAGATCAATCAATTGATTT
CTGGCTATGTGGCAATGGGACAAATCAATACGGAAATCAGCCATGCTTTCTCCGCCTGCGAAAGTGAGGCATACGCCCAT
ATTCGATAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References