Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1443709..1444409 Replicon chromosome
Accession NZ_CP092104
Organism Flagellatimonas centrodinii strain R2A-3

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag JN531_RS06815 Protein ID WP_228348109.1
Coordinates 1444113..1444409 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag JN531_RS06810 Protein ID WP_228348108.1
Coordinates 1443709..1444110 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN531_RS06790 (JN531_006790) 1439690..1440172 + 483 WP_228348104.1 peptidylprolyl isomerase -
JN531_RS06795 (JN531_006795) 1440315..1441181 + 867 WP_228348105.1 methyltransferase -
JN531_RS06800 (JN531_006800) 1441190..1441810 - 621 WP_228348106.1 hypothetical protein -
JN531_RS06805 (JN531_006805) 1441878..1443683 + 1806 WP_228348107.1 acyl-CoA dehydrogenase -
JN531_RS06810 (JN531_006810) 1443709..1444110 - 402 WP_228348108.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
JN531_RS06815 (JN531_006815) 1444113..1444409 - 297 WP_228348109.1 type II toxin-antitoxin system MqsR family toxin Toxin
JN531_RS06820 (JN531_006820) 1444770..1445747 + 978 WP_228348110.1 type I-F CRISPR-associated endonuclease Cas1f -
JN531_RS06825 (JN531_006825) 1445744..1449190 + 3447 WP_228348111.1 type I-F CRISPR-associated helicase Cas3f -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11113.98 Da        Isoelectric Point: 10.4014

>T235700 WP_228348109.1 NZ_CP092104:c1444409-1444113 [Flagellatimonas centrodinii]
VEKRTPHCKLTKVKALVTAGRVRTTQSARLGAVALGLEYTDMLNVLMSLTSADFYKSMTTHGDHRVWQDVYRPRTKAGNV
YLKLTVMEDVLIVSFKER

Download         Length: 297 bp

>T235700 NZ_LR134330:c2002514-2002233 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGTAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCCCTGAAAGCCGTCCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCTTTTCGGGTAAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14387.71 Da        Isoelectric Point: 9.2801

>AT235700 WP_228348108.1 NZ_CP092104:c1444110-1443709 [Flagellatimonas centrodinii]
MKCPACGFAKLVHDTRNLPFTYKGERTVIPAVTGDFCPNCHESVLDASESDRVMGAMKAFTRQVNAAAVDPGFIAGVRKK
LALDQKTAAEIFGGGVNAFSRYETGKTKPPLALVKLLKVLDRHPELLNEIRAG

Download         Length: 402 bp

>AT235700 NZ_LR134330:c2002738-2002511 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCGTATCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References