235650

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2443733..2443917 Replicon chromosome
Accession NZ_CP092072
Organism Staphylococcus argenteus strain 1710042798

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag MCF40_RS11765 Protein ID WP_000482653.1
Coordinates 2443810..2443917 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2443733..2443793 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MCF40_RS11755 2439585..2441318 - 1734 WP_031787186.1 ABC transporter ATP-binding protein -
MCF40_RS11760 2441343..2443106 - 1764 WP_031787187.1 ABC transporter ATP-binding protein -
- 2443733..2443793 + 61 - - Antitoxin
MCF40_RS11765 2443810..2443917 - 108 WP_000482653.1 type I toxin-antitoxin system Fst family toxin Toxin
MCF40_RS11770 2444051..2444437 - 387 WP_000779346.1 flippase GtxA -
MCF40_RS11775 2444705..2445847 + 1143 WP_031787188.1 glycerate kinase -
MCF40_RS11780 2445906..2446565 + 660 WP_000831306.1 membrane protein -
MCF40_RS11785 2446750..2447961 + 1212 WP_031787189.1 multidrug effflux MFS transporter -
MCF40_RS11790 2448077..2448556 - 480 WP_031787190.1 GyrI-like domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sbi / hlgA / hlgA / hlgC / hlgB 2421531..2505647 84116


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 36 a.a.        Molecular weight: 4025.81 Da        Isoelectric Point: 11.0582

>T235650 WP_000482653.1 NZ_CP092072:c2443917-2443810 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T235650 NZ_LR134315:3362067-3362285 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 61 bp

>AT235650 NZ_CP092072:2443733-2443793 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References