Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | SprA2-SprA2AS/- |
Location | 2443733..2443917 | Replicon | chromosome |
Accession | NZ_CP092072 | ||
Organism | Staphylococcus argenteus strain 1710042798 |
Toxin (Protein)
Gene name | SprA2 | Uniprot ID | - |
Locus tag | MCF40_RS11765 | Protein ID | WP_000482653.1 |
Coordinates | 2443810..2443917 (-) | Length | 36 a.a. |
Antitoxin (RNA)
Gene name | SprA2AS | ||
Locus tag | - | ||
Coordinates | 2443733..2443793 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MCF40_RS11755 | 2439585..2441318 | - | 1734 | WP_031787186.1 | ABC transporter ATP-binding protein | - |
MCF40_RS11760 | 2441343..2443106 | - | 1764 | WP_031787187.1 | ABC transporter ATP-binding protein | - |
- | 2443733..2443793 | + | 61 | - | - | Antitoxin |
MCF40_RS11765 | 2443810..2443917 | - | 108 | WP_000482653.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
MCF40_RS11770 | 2444051..2444437 | - | 387 | WP_000779346.1 | flippase GtxA | - |
MCF40_RS11775 | 2444705..2445847 | + | 1143 | WP_031787188.1 | glycerate kinase | - |
MCF40_RS11780 | 2445906..2446565 | + | 660 | WP_000831306.1 | membrane protein | - |
MCF40_RS11785 | 2446750..2447961 | + | 1212 | WP_031787189.1 | multidrug effflux MFS transporter | - |
MCF40_RS11790 | 2448077..2448556 | - | 480 | WP_031787190.1 | GyrI-like domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | sbi / hlgA / hlgA / hlgC / hlgB | 2421531..2505647 | 84116 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 4025.81 Da Isoelectric Point: 11.0582
>T235650 WP_000482653.1 NZ_CP092072:c2443917-2443810 [Staphylococcus argenteus]
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK
MFNLLINIMTTAISGCLVAFFAHWLRTRNNKKGDK
Download Length: 108 bp
>T235650 NZ_LR134315:3362067-3362285 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
Antitoxin
Download Length: 61 bp
>AT235650 NZ_CP092072:2443733-2443793 [Staphylococcus argenteus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|