Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
| Location | 4879988..4881339 | Replicon | chromosome |
| Accession | NZ_CP092039 | ||
| Organism | Pectobacterium brasiliense strain 130 | ||
Toxin (Protein)
| Gene name | HipT | Uniprot ID | - |
| Locus tag | MBA20_RS21515 | Protein ID | WP_119871557.1 |
| Coordinates | 4880299..4881339 (+) | Length | 347 a.a. |
Antitoxin (Protein)
| Gene name | HipS | Uniprot ID | A0A086EBR8 |
| Locus tag | MBA20_RS21510 | Protein ID | WP_039279922.1 |
| Coordinates | 4879988..4880302 (+) | Length | 105 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MBA20_RS21485 (MBA20_21485) | 4875785..4876819 | + | 1035 | WP_119871561.1 | putative FMN-dependent luciferase-like monooxygenase | - |
| MBA20_RS21490 (MBA20_21490) | 4876816..4877949 | + | 1134 | WP_119871560.1 | alkylhydroperoxidase domain protein | - |
| MBA20_RS21495 (MBA20_21495) | 4878006..4878518 | - | 513 | WP_185893742.1 | phenolic acid decarboxylase | - |
| MBA20_RS21500 (MBA20_21500) | 4878618..4879490 | + | 873 | WP_119871558.1 | LysR family transcriptional regulator | - |
| MBA20_RS21505 (MBA20_21505) | 4879677..4880003 | + | 327 | WP_039510297.1 | helix-turn-helix domain-containing protein | - |
| MBA20_RS21510 (MBA20_21510) | 4879988..4880302 | + | 315 | WP_039279922.1 | HipA N-terminal domain-containing protein | Antitoxin |
| MBA20_RS21515 (MBA20_21515) | 4880299..4881339 | + | 1041 | WP_119871557.1 | HipA domain-containing protein | Toxin |
| MBA20_RS21520 (MBA20_21520) | 4881399..4882022 | - | 624 | WP_119871556.1 | LysE family translocator | - |
| MBA20_RS21525 (MBA20_21525) | 4882290..4883045 | + | 756 | WP_119871555.1 | thiol:disulfide interchange protein DsbG | - |
| MBA20_RS21530 (MBA20_21530) | 4883079..4883984 | - | 906 | WP_119871554.1 | siderophore-interacting protein | - |
| MBA20_RS21535 (MBA20_21535) | 4884239..4884490 | + | 252 | WP_010281712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| MBA20_RS21540 (MBA20_21540) | 4884487..4884774 | + | 288 | WP_015842269.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| MBA20_RS21545 (MBA20_21545) | 4884892..4886244 | - | 1353 | WP_119871553.1 | glutathione-disulfide reductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 347 a.a. Molecular weight: 39677.65 Da Isoelectric Point: 6.4479
>T235546 WP_119871557.1 NZ_CP092039:4880299-4881339 [Pectobacterium brasiliense]
MTRCRILLTPLTHEEEIATGYSRKGLKHLAGKMHTSPDLRFTRQQFMHDLPQAQKGMSISGYQPKIQLVLEEQAFTVVDH
QGLYILKHSPIEFPYLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKTHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLMHLRSGQLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADLTKEAECVETTYRDSFMP
ADAIETTLRCYRHRLNLMSILDAERI
MTRCRILLTPLTHEEEIATGYSRKGLKHLAGKMHTSPDLRFTRQQFMHDLPQAQKGMSISGYQPKIQLVLEEQAFTVVDH
QGLYILKHSPIEFPYLAENEHATMTLMARLGFAVPPHGLLRFKPEQADDEPEFAFVIKRFDRDEKTGHPIHQEQLDGAMG
IGEKFGKTHTDGRQYVSYERLALFLSKHVNDNIVFKIDLFRRIAYAYMLGNNDMHLRNFGLMHLRSGQLMLAPIYDFVSV
APYPTYFSSCFMALPLLIQEEGDEALAPGFETAYGEYLGMDFILFGQRIGLSENLTKKLLADLTKEAECVETTYRDSFMP
ADAIETTLRCYRHRLNLMSILDAERI
Download Length: 1041 bp
>T235546 NZ_LR134302:c5759050-5758616 [Achromobacter spanius]
ATGATTCTGCTGGACACCAATGTCATTTCGGAACCGCTGCGCCAAGCGCCCGCCGACGCCGTCATCGAATGGATAGACCG
GCAGCCCTTGGAAACCCTGTTCCTTTCCGCCGTCACCGTCGCTGAATTGCGGTTTGGCGTCGCCTGCATGCCAGTGGGCA
AACGGCGCGACGCCTTGCATGGCGACCTGGAACAGCGCGTGCTGGCCTTGTTTGCCGGGCGCGTCCTGGCTTTCGACACC
GCCGCCAGCCTGGAATACGCCACGTTGATGGCGCGCGCGCGGGCTTCGGGCCAGTCCATCGGCGGGCCAGACGGCTACAT
CGCCGCCACCGCCGCCGCGCACGGCATGAGCGTGGCCACCCGGGACATTGCGCCCTTTGAAGCCGCGGGCGTTTCCGTCA
TCAACCCTTGGGGCGCCTCGCACCCGCCGCACTAG
ATGATTCTGCTGGACACCAATGTCATTTCGGAACCGCTGCGCCAAGCGCCCGCCGACGCCGTCATCGAATGGATAGACCG
GCAGCCCTTGGAAACCCTGTTCCTTTCCGCCGTCACCGTCGCTGAATTGCGGTTTGGCGTCGCCTGCATGCCAGTGGGCA
AACGGCGCGACGCCTTGCATGGCGACCTGGAACAGCGCGTGCTGGCCTTGTTTGCCGGGCGCGTCCTGGCTTTCGACACC
GCCGCCAGCCTGGAATACGCCACGTTGATGGCGCGCGCGCGGGCTTCGGGCCAGTCCATCGGCGGGCCAGACGGCTACAT
CGCCGCCACCGCCGCCGCGCACGGCATGAGCGTGGCCACCCGGGACATTGCGCCCTTTGAAGCCGCGGGCGTTTCCGTCA
TCAACCCTTGGGGCGCCTCGCACCCGCCGCACTAG
Antitoxin
Download Length: 105 a.a. Molecular weight: 11898.74 Da Isoelectric Point: 9.8041
>AT235546 WP_039279922.1 NZ_CP092039:4879988-4880302 [Pectobacterium brasiliense]
MRRQVKVYLYGVHIGQLSQDDKGYLFEYKKSYIGPPLSLSLPIQTGTFRSRTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKA
MRRQVKVYLYGVHIGQLSQDDKGYLFEYKKSYIGPPLSLSLPIQTGTFRSRTLPPYFASLAPEGWLRRQYSQLQHLDEKD
LFGILIQNGKNLIGAVQLIAEDKA
Download Length: 315 bp
>AT235546 NZ_LR134302:c5759298-5759047 [Achromobacter spanius]
ATGCCCATGTTGACCGTTAGAAATATCTCTGAAGAAGTGCACCGCGCGCTGCGCGTGCGCGCCGCCCAGCATGGCCGAAG
CACCGAAGCCGAGGTCCGCGCCATTCTTGAAGACGCCGTCAAGCCTGAAGGGCGCGTCAAGCTGGGCTCGTTGCTTGCGC
AGATCGGCCGCCAGGCCAAGCTCACCGAAGAGGAAGCCGCCTTGTTCGACCAACGCGACAAGGCGCCCGCCGCCCCACCG
AGGTTTGAATGA
ATGCCCATGTTGACCGTTAGAAATATCTCTGAAGAAGTGCACCGCGCGCTGCGCGTGCGCGCCGCCCAGCATGGCCGAAG
CACCGAAGCCGAGGTCCGCGCCATTCTTGAAGACGCCGTCAAGCCTGAAGGGCGCGTCAAGCTGGGCTCGTTGCTTGCGC
AGATCGGCCGCCAGGCCAAGCTCACCGAAGAGGAAGCCGCCTTGTTCGACCAACGCGACAAGGCGCCCGCCGCCCCACCG
AGGTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|