Detailed information of TA system TA023532

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 2727226..2727759
• Replicon: chromosome
• Accession: NC_011989
• Organism: Agrobacterium vitis S4

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: B9JZQ2
• Locus tag: AVI_RS13010
• Protein ID: WP_015916781.1
• Coordinates: 2727493..2727759 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: B9JZQ1
• Locus tag: AVI_RS13005
• Protein ID: WP_015916780.1
• Coordinates: 2727226..2727489 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AVI_RS12985	2722539..2723645	+	1107	WP_015916776.1	branched-chain amino acid ABC transporter substrate-binding protein	-
AVI_RS12990	2723929..2724798	+	870	WP_015916777.1	aldose 1-epimerase family protein	-
AVI_RS12995	2724795..2725457	+	663	WP_015916778.1	chloramphenicol phosphotransferase	-
AVI_RS13000	2725477..2727171	+	1695	WP_015916779.1	adenine deaminase	-
AVI_RS13005	2727226..2727489	+	264	WP_015916780.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
AVI_RS13010	2727493..2727759	+	267	WP_015916781.1	Txe/YoeB family addiction module toxin	Toxin
AVI_RS13015	2727767..2729443	-	1677	WP_139192432.1	alpha glucosidase	-
AVI_RS13020	2729711..2730778	+	1068	WP_015916783.1	glycosyltransferase family 1 protein	-
AVI_RS13025	2730798..2732222	-	1425	WP_015916784.1	ribosome biogenesis GTPase Der	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10361.77 Da
• Isoelectric Point: 8.4926

>T23532 WP_015916781.1 NC_011989:2727493-2727759 [Agrobacterium vitis S4]
MLVAFTDEGWEDYCFWQETDPKTAQRINALLKDTKRHPFSGIGKPEPLKGQFKGFWSRRISQEHRLVYAVKGQDSDQVLI
VAQCRYHY

Nucleotide

• Length: 267 bp

>T23532 NC_011989:2727493-2727759 [Agrobacterium vitis S4]
ATGCTGGTCGCCTTTACAGATGAAGGCTGGGAAGATTACTGCTTCTGGCAGGAAACCGATCCCAAAACGGCGCAGCGGAT
CAATGCCCTGCTAAAGGACACCAAACGCCATCCCTTTTCCGGCATTGGCAAGCCAGAGCCACTGAAAGGCCAGTTCAAAG
GCTTCTGGTCACGCCGCATCAGCCAGGAACACCGCCTGGTTTATGCGGTGAAAGGTCAGGATAGCGATCAAGTGCTGATC
GTGGCGCAATGCCGCTATCATTATTGA

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9598.93 Da
• Isoelectric Point: 5.1358

>AT23532 WP_015916780.1 NC_011989:2727226-2727489 [Agrobacterium vitis S4]
MDTVFFSKARAELAGLLDKVNEDASAVEIVRRDKPSAVLMSKEEYESMVETLHLLSSPANASRLLKAKQAIEAGRFSPRH
LPDLDDA

Nucleotide

• Length: 264 bp

>AT23532 NC_011989:2727226-2727489 [Agrobacterium vitis S4]
ATGGACACTGTGTTTTTTTCCAAAGCCCGGGCCGAACTGGCCGGGCTGCTCGACAAGGTGAACGAGGATGCATCGGCTGT
GGAGATCGTGCGCCGGGACAAGCCCTCTGCCGTGCTTATGAGCAAGGAAGAATATGAGAGCATGGTGGAAACTCTGCATC
TCCTCTCCTCGCCCGCCAATGCCAGCCGTCTGCTGAAGGCGAAACAGGCTATAGAAGCAGGCCGCTTTTCCCCGCGCCAC
CTCCCTGATCTGGATGACGCCTGA

Structures

Toxin

• AlphaFold DB: B9JZQ2

Antitoxin

• AlphaFold DB: B9JZQ1