Detailed information of TA system TA235237

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-ratA/Fst(toxin)
• Location: 147320..147561
• Replicon: plasmid p1
• Accession: NZ_CP091907
• Organism: Enterococcus faecalis strain 2-1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: L5I26_RS13975
• Protein ID: WP_002360667.1
• Coordinates: 147320..147430 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	147470..147561 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5I26_RS13960 (142780)	142780..143130	+	351	WP_002400993.1	hypothetical protein	-
L5I26_RS13965 (143365)	143365..146337	-	2973	Protein_161	Tn3 family transposase	-
L5I26_RS13970 (146468)	146468..147073	+	606	WP_000238804.1	recombinase family protein	-
L5I26_RS13975 (147320)	147320..147430	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (147470)	147470..147561	-	92	NuclAT_0	-	Antitoxin
- (147470)	147470..147561	-	92	NuclAT_0	-	Antitoxin
- (147470)	147470..147561	-	92	NuclAT_0	-	Antitoxin
- (147470)	147470..147561	-	92	NuclAT_0	-	Antitoxin
L5I26_RS13980 (147670)	147670..147960	+	291	WP_049084802.1	hypothetical protein	-
L5I26_RS13985 (148064)	148064..148435	-	372	WP_000049959.1	replication-associated protein RepC	-
L5I26_RS13990 (148428)	148428..149273	-	846	WP_000239313.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	aph(3')-III / erm(B)	cylR2 / cylR1 / cylL / cylS / cylM / cylB / cylA / cylI / EF0149 / asa1	1..149744	149744

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T235237 WP_002360667.1 NZ_CP091907:147320-147430 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T235237 NZ_LR134231:c602843-602379 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAAACAGAAGAAACCCATTGA

Antitoxin

Nucleotide

• Length: 92 bp

>AT235237 NZ_CP091907:c147561-147470 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin