Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-ratA/- |
Location | 2493500..2493723 | Replicon | chromosome |
Accession | NZ_CP091906 | ||
Organism | Enterococcus faecalis strain 2-1 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | - |
Locus tag | L5I26_RS11985 | Protein ID | WP_075551663.1 |
Coordinates | 2493622..2493723 (-) | Length | 34 a.a. |
Antitoxin (RNA)
Gene name | ratA | ||
Locus tag | - | ||
Coordinates | 2493500..2493677 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L5I26_RS11960 | 2489147..2490100 | - | 954 | WP_002375576.1 | siderophore ABC transporter substrate-binding protein | - |
L5I26_RS11965 | 2490139..2490894 | - | 756 | WP_002354962.1 | ATP-binding cassette domain-containing protein | - |
L5I26_RS11970 | 2490891..2491856 | - | 966 | WP_002371665.1 | iron chelate uptake ABC transporter family permease subunit | - |
L5I26_RS11975 | 2491853..2492800 | - | 948 | WP_010716775.1 | iron chelate uptake ABC transporter family permease subunit | - |
L5I26_RS11980 | 2492985..2493437 | + | 453 | WP_002354958.1 | YueI family protein | - |
- | 2493500..2493677 | + | 178 | - | - | Antitoxin |
L5I26_RS11985 | 2493622..2493723 | - | 102 | WP_075551663.1 | putative holin-like toxin | Toxin |
L5I26_RS11990 | 2494055..2494156 | - | 102 | WP_075551663.1 | putative holin-like toxin | - |
L5I26_RS11995 | 2494346..2496616 | - | 2271 | WP_002398160.1 | bifunctional glutamate--cysteine ligase/glutathione synthetase | - |
L5I26_RS12000 | 2496787..2497287 | + | 501 | WP_002365352.1 | cysteine hydrolase family protein | - |
L5I26_RS12005 | 2497590..2498486 | + | 897 | WP_002354953.1 | YitT family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 34 a.a. Molecular weight: 3599.34 Da Isoelectric Point: 4.5869
>T235210 WP_075551663.1 NZ_CP091906:c2493723-2493622 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK
MSIEAALELMISFAAFVALLIFGILEATKNDKK
Download Length: 102 bp
>T235210 NZ_LR134227:c4104631-4104458 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCGTTACTTT
TTTCTCTCTTTTAG
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCGTTACTTT
TTTCTCTCTTTTAG
Antitoxin
Download Length: 178 bp
>AT235210 NZ_CP091906:2493500-2493677 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAGCGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAGCGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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