Detailed information of TA system TA235189

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 319413..319607
• Replicon: chromosome
• Accession: NZ_CP091904
• Organism: Enterococcus faecalis strain 43-2

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: L5I20_RS01615
• Protein ID: WP_015543884.1
• Coordinates: 319512..319607 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	319413..319477 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5I20_RS01600	315031..316773	+	1743	WP_002385355.1	PTS transporter subunit EIIC	-
L5I20_RS01605	316764..318797	+	2034	WP_002361171.1	PRD domain-containing protein	-
L5I20_RS01610	318808..319242	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	319413..319477	+	65	-	-	Antitoxin
L5I20_RS01615	319512..319607	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
L5I20_RS01620	319853..321625	+	1773	WP_238461513.1	PTS mannitol-specific transporter subunit IIBC	-
L5I20_RS01625	321640..322077	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
L5I20_RS01630	322092..323246	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
L5I20_RS01635	323313..324428	-	1116	WP_002380024.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T235189 WP_015543884.1 NZ_CP091904:c319607-319512 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T235189 NZ_LR134226:c4531130-4530819 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT235189 NZ_CP091904:319413-319477 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin