Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/Fst(toxin)
Location 41347..41588 Replicon plasmid p2
Accession NZ_CP091903
Organism Enterococcus faecalis strain 59

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag L5I17_RS15730 Protein ID WP_002360667.1
Coordinates 41347..41457 (+) Length 37 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 41497..41588 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L5I17_RS15705 (36485) 36485..39457 - 2973 WP_000653331.1 Tn3 family transposase -
L5I17_RS15710 (39588) 39588..40193 + 606 WP_000238804.1 recombinase family protein -
L5I17_RS15715 (40255) 40255..40749 + 495 Protein_42 excinuclease ABC subunit A -
L5I17_RS15720 (40746) 40746..41096 + 351 WP_002360672.1 hypothetical protein -
L5I17_RS15725 (41053) 41053..41265 + 213 WP_002360669.1 hypothetical protein -
L5I17_RS15730 (41347) 41347..41457 + 111 WP_002360667.1 type I toxin-antitoxin system Fst family toxin Toxin
- (41497) 41497..41588 - 92 NuclAT_0 - Antitoxin
- (41497) 41497..41588 - 92 NuclAT_0 - Antitoxin
- (41497) 41497..41588 - 92 NuclAT_0 - Antitoxin
- (41497) 41497..41588 - 92 NuclAT_0 - Antitoxin
L5I17_RS15735 (41697) 41697..41987 + 291 WP_001137528.1 hypothetical protein -
L5I17_RS15740 (42091) 42091..42462 - 372 WP_000049959.1 replication-associated protein RepC -
L5I17_RS15745 (42455) 42455..43300 - 846 WP_000239313.1 AAA family ATPase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid VanHAX - 1..43739 43739


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 37 a.a.        Molecular weight: 4117.92 Da        Isoelectric Point: 4.1672

>T235188 WP_002360667.1 NZ_CP091903:41347-41457 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Download         Length: 111 bp

>T235188 NZ_LR134226:c4254162-4253989 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 92 bp

>AT235188 NZ_CP091903:c41588-41497 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References