Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | fst-RNAII/Fst(toxin) |
Location | 41347..41588 | Replicon | plasmid p2 |
Accession | NZ_CP091903 | ||
Organism | Enterococcus faecalis strain 59 |
Toxin (Protein)
Gene name | fst | Uniprot ID | - |
Locus tag | L5I17_RS15730 | Protein ID | WP_002360667.1 |
Coordinates | 41347..41457 (+) | Length | 37 a.a. |
Antitoxin (RNA)
Gene name | RNAII | ||
Locus tag | - | ||
Coordinates | 41497..41588 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L5I17_RS15705 (36485) | 36485..39457 | - | 2973 | WP_000653331.1 | Tn3 family transposase | - |
L5I17_RS15710 (39588) | 39588..40193 | + | 606 | WP_000238804.1 | recombinase family protein | - |
L5I17_RS15715 (40255) | 40255..40749 | + | 495 | Protein_42 | excinuclease ABC subunit A | - |
L5I17_RS15720 (40746) | 40746..41096 | + | 351 | WP_002360672.1 | hypothetical protein | - |
L5I17_RS15725 (41053) | 41053..41265 | + | 213 | WP_002360669.1 | hypothetical protein | - |
L5I17_RS15730 (41347) | 41347..41457 | + | 111 | WP_002360667.1 | type I toxin-antitoxin system Fst family toxin | Toxin |
- (41497) | 41497..41588 | - | 92 | NuclAT_0 | - | Antitoxin |
- (41497) | 41497..41588 | - | 92 | NuclAT_0 | - | Antitoxin |
- (41497) | 41497..41588 | - | 92 | NuclAT_0 | - | Antitoxin |
- (41497) | 41497..41588 | - | 92 | NuclAT_0 | - | Antitoxin |
L5I17_RS15735 (41697) | 41697..41987 | + | 291 | WP_001137528.1 | hypothetical protein | - |
L5I17_RS15740 (42091) | 42091..42462 | - | 372 | WP_000049959.1 | replication-associated protein RepC | - |
L5I17_RS15745 (42455) | 42455..43300 | - | 846 | WP_000239313.1 | AAA family ATPase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | VanHAX | - | 1..43739 | 43739 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 37 a.a. Molecular weight: 4117.92 Da Isoelectric Point: 4.1672
>T235188 WP_002360667.1 NZ_CP091903:41347-41457 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK
Download Length: 111 bp
>T235188 NZ_LR134226:c4254162-4253989 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG
Antitoxin
Download Length: 92 bp
>AT235188 NZ_CP091903:c41588-41497 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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