Detailed information of TA system TA235185

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 41347..41561
• Replicon: plasmid p2
• Accession: NZ_CP091903
• Organism: Enterococcus faecalis strain 59

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: L5I17_RS15730
• Protein ID: WP_002360667.1
• Coordinates: 41347..41457 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	41497..41561 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5I17_RS15705	36485..39457	-	2973	WP_000653331.1	Tn3 family transposase	-
L5I17_RS15710	39588..40193	+	606	WP_000238804.1	recombinase family protein	-
L5I17_RS15715	40255..40749	+	495	Protein_42	excinuclease ABC subunit A	-
L5I17_RS15720	40746..41096	+	351	WP_002360672.1	hypothetical protein	-
L5I17_RS15725	41053..41265	+	213	WP_002360669.1	hypothetical protein	-
L5I17_RS15730	41347..41457	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	41497..41561	-	65	-	-	Antitoxin
L5I17_RS15735	41697..41987	+	291	WP_001137528.1	hypothetical protein	-
L5I17_RS15740	42091..42462	-	372	WP_000049959.1	replication-associated protein RepC	-
L5I17_RS15745	42455..43300	-	846	WP_000239313.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	VanHAX	-	1..43739	43739

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T235185 WP_002360667.1 NZ_CP091903:41347-41457 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T235185 NZ_LR134226:3499125-3499667 [Escherichia coli]
ATGGTCGACAAGCATGAAGAGATTACTCTGCCCATAGTCCTCTCCTGTAATTATCAGTCTGATATTACTTATCCTGGGCA
AAAACAGTTTGATTGCGGTAACCCTGTTATCGATAAATTTGTACGCGCATCGCTAAAGAAAAGTGTGCGTAATAGCGACT
GTGCGGCTAAAGCACTTATTGACAGACAAAGTGGTGAACTGATCGGCATCTGTACTTTTACGGCATATTCGCTGGAAAAA
CAACGCGTTTCTGGCGTCCTTCAGGGTTCACAACCTTCAGAAATTGGTGTTGTCAGATTAGTCATGTTGGGGGTAGCACG
GAAGTATCAAAAGCGGGGCTTTGGTCAGGACCTACTATGTGATTTTTTTGAACATGTAAAAATAATTCACCAGGCATTAC
CAATTAAAGGGGTTTATCTTGATGCTGACCCTGCCGCCATTAATTTTTATGCTCGTCTCGGCTTTGTTCAGCTTTCAGCG
ACACCAAATGCTTTTGGTGCTGTACCTATGTTTTTGGCGATTCAGCATATTCTCGCGGCTTAG

Antitoxin

Nucleotide

• Length: 65 bp

>AT235185 NZ_CP091903:c41561-41497 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin