Detailed information of TA system TA235123

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 323620..323814
• Replicon: chromosome
• Accession: NZ_CP091899
• Organism: Enterococcus faecalis strain 101-1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: L5I21_RS01640
• Protein ID: WP_015543884.1
• Coordinates: 323719..323814 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	323620..323684 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5I21_RS01625	319253..320995	+	1743	WP_002399652.1	PTS transporter subunit EIIC	-
L5I21_RS01630	320986..323019	+	2034	WP_002387671.1	PRD domain-containing protein	-
L5I21_RS01635	323030..323464	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
-	323620..323684	+	65	-	-	Antitoxin
L5I21_RS01640	323719..323814	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
L5I21_RS01645	324060..325832	+	1773	WP_010706745.1	PTS mannitol-specific transporter subunit IIBC	-
L5I21_RS01650	325847..326284	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
L5I21_RS01655	326299..327453	+	1155	WP_002355280.1	mannitol-1-phosphate 5-dehydrogenase	-
L5I21_RS01660	327520..328635	-	1116	WP_002379062.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T235123 WP_015543884.1 NZ_CP091899:c323814-323719 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T235123 NZ_LR134216:2615694-2615801 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT235123 NZ_CP091899:323620-323684 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Structures

Antitoxin