Detailed information of TA system TA235050

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/-
• Location: 318703..318898
• Replicon: chromosome
• Accession: NZ_CP091892
• Organism: Enterococcus faecalis strain 133-1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: L5I22_RS01635
• Protein ID: WP_015543884.1
• Coordinates: 318803..318898 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	318703..318768 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5I22_RS01620 (314329)	314329..316077	+	1749	WP_002397549.1	PTS transporter subunit EIIC	-
L5I22_RS01625 (316068)	316068..318101	+	2034	WP_002397548.1	BglG family transcription antiterminator	-
L5I22_RS01630 (318112)	318112..318546	+	435	WP_002358391.1	PTS sugar transporter subunit IIA	-
- (318703)	318703..318768	+	66	NuclAT_17	-	Antitoxin
L5I22_RS01635 (318803)	318803..318898	-	96	WP_015543884.1	type I toxin-antitoxin system Fst family toxin	Toxin
L5I22_RS01640 (319144)	319144..320916	+	1773	WP_002405272.1	PTS mannitol-specific transporter subunit IIBC	-
L5I22_RS01645 (320931)	320931..321368	+	438	WP_002355279.1	PTS sugar transporter subunit IIA	-
L5I22_RS01650 (321383)	321383..322537	+	1155	WP_002386082.1	mannitol-1-phosphate 5-dehydrogenase	-
L5I22_RS01655 (322606)	322606..323721	-	1116	WP_002397546.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3659.47 Da
• Isoelectric Point: 4.6275

>T235050 WP_015543884.1 NZ_CP091892:c318898-318803 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Nucleotide

• Length: 96 bp

>T235050 NZ_LR134196:c4578962-4578681 [Klebsiella quasipneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGCTTGGCGAGACGGTCAAAAAACAGTTCAAAAA
TAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGGCCAGGCTGAGCGATTTGCCGGATTGCTACAAAATCAAGC
TTAAGGCGTCAGGTTATCGGCTGGTGTATCAAGTACGAGATAGGGTGGTGGTGGTTTACGTTATTGCCATTGGCAAAAGA
GAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin

Nucleotide

• Length: 66 bp

>AT235050 NZ_CP091892:318703-318768 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATCAGTAGTAGGGTGTCTTTTTTT

Structures

Antitoxin