Detailed information of TA system TA235048

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 74982..75223
• Replicon: plasmid p1
• Accession: NZ_CP091890
• Organism: Enterococcus faecalis strain 142-1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: L5I18_RS16335
• Protein ID: WP_002360667.1
• Coordinates: 74982..75092 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	75132..75223 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5I18_RS16285 (70107)	70107..70469	-	363	WP_000241511.1	type II toxin-antitoxin system PemK/MazF family toxin	-
L5I18_RS16290 (70463)	70463..70726	-	264	WP_000245205.1	PbsX family transcriptional regulator	-
L5I18_RS16295 (70903)	70903..71523	+	621	WP_021732893.1	recombinase family protein	-
L5I18_RS16300 (71540)	71540..71827	+	288	WP_010708491.1	hypothetical protein	-
L5I18_RS16305 (71821)	71821..72045	+	225	WP_010708492.1	ultraviolet resistance protein UvrA repressor UvrC	-
L5I18_RS16310 (72106)	72106..72315	+	210	WP_002387638.1	hypothetical protein	-
L5I18_RS16315 (72477)	72477..72629	+	153	WP_225850000.1	DUF6440 family protein	-
L5I18_RS16320 (73056)	73056..74384	+	1329	WP_021732894.1	ultraviolet resistance protein UvrA	-
L5I18_RS16325 (74381)	74381..74731	+	351	WP_002399364.1	hypothetical protein	-
L5I18_RS16330 (74688)	74688..74900	+	213	WP_002360669.1	hypothetical protein	-
L5I18_RS16335 (74982)	74982..75092	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (75132)	75132..75223	-	92	NuclAT_0	-	Antitoxin
- (75132)	75132..75223	-	92	NuclAT_0	-	Antitoxin
- (75132)	75132..75223	-	92	NuclAT_0	-	Antitoxin
- (75132)	75132..75223	-	92	NuclAT_0	-	Antitoxin
L5I18_RS16340 (75332)	75332..75628	+	297	WP_002360665.1	replication control protein PrgN	-
L5I18_RS16345 (75882)	75882..76664	+	783	WP_002360664.1	ParA family protein	-
L5I18_RS16350 (76657)	76657..77013	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	prgB/asc10	1..77272	77272

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T235048 WP_002360667.1 NZ_CP091890:74982-75092 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T235048 NZ_LR134196:c2506128-2504806 [Klebsiella quasipneumoniae]
ATGGCGACGCTCACCACCTGGATGAACAATGCGCGCGTGGGAACCTTAACCCGCCAGGCCAACGGGGCGCACAGTTTCCG
CTATGATGAGGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCGCTGCCGCTGCAGTATGGCAATATTACCG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGAGCGGATCGTCAGGCGCTATCAG
GCGCGTTCGAAACAGCCGTTCGATCTGCTGGCCGAGGTCGGGCGGGACAGCGTAGGGGCGGTGACTCTGCTGCCGCCGGG
GGAAGAGGCGCATCTTGCCGCGTTGCGCTGGCAGACGCTGGATGAGGCGCAGCTGACCGCTTTGCTGACCGCCTACCAGT
CGGATATTCCTCTCGGGATGGTGACCGGCCAGGACGATTTTCGGATCTCGGTGGCCGGCGCTCAGGAGAAAACCGCGCTG
CTGCGAATGGGCGAGCACTGGTGTATTCCGCAGGGCACCACCCCGACCACCCATATCATTAAACTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAACGAATATCTGTGCCTGGCGCTGGCCAGGGCGTTGG
GCCTGGCGGTGCCGGAGGCGGAGATTATCAACACGCCGCGGATCCGTGCGCTGGCGGTGACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGGCGCGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCATTCGGCATACCGTCGTCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGTTCCAGTGAGGCCCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTGTTCCAGTGGCTGACCGGGGCAACGGACGGGCATGCGAAGAACTTCTCGCTCTTTTTGCTG
CCCGGCGGCAGCTACCGGCTCACGCCGTTCTACGACATTATTTCGGCATTTCCGGTGCTGGGCGGGACGGGACTGCATCT
GCGCGACCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGGAAAACGGAGATTAACGCTATCTATCCGCGTCATT
TTCTGGCGACCGCCAAAGCGGTTAACTTCCCCCGGGAGCAGATGCTGGCGATCCTGGGCGAGTTTGCCGACCGCGTGCCG
CAGGCCATCGAAAGCGCCCGCCGGACGCTGCCGTCGGACTTTTCCGCCCACGTCTGGCGGGCCATCACGGAGAACATGCT
GAAACTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGGGATAG

Antitoxin

Nucleotide

• Length: 92 bp

>AT235048 NZ_CP091890:c75223-75132 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin