Detailed information of TA system TA235017

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 66480..66694
• Replicon: plasmid p1
• Accession: NZ_CP091887
• Organism: Enterococcus faecalis strain 143-1

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: L5I19_RS14625
• Protein ID: WP_002360667.1
• Coordinates: 66480..66590 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	66630..66694 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5I19_RS14580	61665..61871	+	207	Protein_66	transposase	-
L5I19_RS14585	62401..63021	+	621	WP_021732893.1	recombinase family protein	-
L5I19_RS14590	63038..63325	+	288	WP_010708491.1	hypothetical protein	-
L5I19_RS14595	63319..63543	+	225	WP_010708492.1	ultraviolet resistance protein UvrA repressor UvrC	-
L5I19_RS14600	63604..63813	+	210	WP_002387638.1	hypothetical protein	-
L5I19_RS14605	63975..64127	+	153	WP_225850000.1	DUF6440 family protein	-
L5I19_RS14610	64554..65882	+	1329	WP_021732894.1	ultraviolet resistance protein UvrA	-
L5I19_RS14615	65879..66229	+	351	WP_002399364.1	hypothetical protein	-
L5I19_RS14620	66186..66398	+	213	WP_002360669.1	hypothetical protein	-
L5I19_RS14625	66480..66590	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	66630..66694	-	65	-	-	Antitoxin
L5I19_RS14630	66830..67126	+	297	WP_002360665.1	replication control protein PrgN	-
L5I19_RS14635	67380..68162	+	783	WP_002360664.1	ParA family protein	-
L5I19_RS14640	68155..68511	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	prgB/asc10	1..68770	68770

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T235017 WP_002360667.1 NZ_CP091887:66480-66590 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

>T235017 NZ_LR134189:c875990-875787 [Providencia rustigianii]
ATGACCAAATCTGATTATCTGATGCGTTTGAGAAAATGCACAACTCTTGAAACACTTGAGCGCGTCATTGAAAAAAATAA
ATATGAGTTATCAGATGATGAGTTAGAGTTATTTTACTCTGCTGCAGACCACCGTCTTGCAGAGCTCACCATGAATAAAC
TTTACGATAAGATCCCTCCATCTGTTTGGAAGTTTGTTAGATAA

Antitoxin

Nucleotide

• Length: 65 bp

>AT235017 NZ_CP091887:c66694-66630 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin