Detailed information of TA system TA234987

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2708855..2709116
• Replicon: chromosome
• Accession: NZ_CP091884
• Organism: Enterococcus faecalis strain 152

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: L5I24_RS13285
• Protein ID: WP_224561205.1
• Coordinates: 2709015..2709116 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2708855..2709066 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5I24_RS13260	2704539..2705492	-	954	WP_002359060.1	siderophore ABC transporter substrate-binding protein	-
L5I24_RS13265	2705531..2706286	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
L5I24_RS13270	2706283..2707248	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
L5I24_RS13275	2707245..2708192	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
L5I24_RS13280	2708377..2708829	+	453	WP_002378807.1	YueI family protein	-
-	2708855..2709066	+	212	-	-	Antitoxin
L5I24_RS13285	2709015..2709116	-	102	WP_224561205.1	putative holin-like toxin	Toxin
L5I24_RS13290	2709307..2711577	-	2271	WP_002378809.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
L5I24_RS13295	2711748..2712254	+	507	WP_002378810.1	cysteine hydrolase family protein	-
L5I24_RS13300	2712444..2713340	+	897	WP_002365354.1	YitT family protein	-
L5I24_RS13305	2713391..2713789	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3629.37 Da
• Isoelectric Point: 4.5869

>T234987 WP_224561205.1 NZ_CP091884:c2709116-2709015 [Enterococcus faecalis]
MSIEATLELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

>T234987 NZ_LR134167:c562380-562057 [Avibacterium volantium]
ATGAAATCAACAAATATTAATGAAGCAGCAATAGATGCTCTTGGCTTGAAGCCTTTTGATGTGGCTGAATATTTGAATGA
TGAAGAAACTATTCAAGCATATTTAATGGAAGTGCTAAAAGAAGGTAATCAAGATGAATTTTTAGAAGCCTTAAGCGATG
TCGCAAGAGCAAGAGGAATGACGGAGCTGGCTAAACAAACGGGTTTAGGGCGTGAAAGTTTGTATAAAACCCTATCCAAA
GGCAGTAAACCGAGATTTGAAACCATACAAAAAATTCTCGCGGCGTTTAATTTGGAACTCGTGCCAACAATTAAAGTGCG
GTGA

Antitoxin

Nucleotide

• Length: 212 bp

>AT234987 NZ_CP091884:2708855-2709066 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAAC
ACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGG
TTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin